Sarawoot PalipochPhanit KoomhinChuchard PunsawadPrasit SuwannalertWalailak UniversityMahidol University2020-01-272020-01-272019-05-01Tropical Journal of Pharmaceutical Research. Vol.18, No.5 (2019), 114915969827159659962-s2.0-85068790202https://repository.li.mahidol.ac.th/handle/20.500.14594/51678© Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria. All rights reserved. A wrong abstract was inadvertently published in the above article. This error is highly regretted. The correct abstract is published below. Purpose: To investigate the antioxidant and anti-inflammatory effects of aqueous leaf extract of T. laurifolia against alcoholic liver injury in rats. Methods: Male Wistar rats were administered either normal saline, ethanol (EtOH), normal saline with low or high dose T. laurifolia leaf extract (TL-LD or TL-HD), EtOH with TL-LD or EtOH with TL-HD. Blood biochemical indices: hepatic malondialdehyde (MDA) levels, liver histopathology, hepatic cytochrome P450 2E1 (CYP2E1), nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, and pro-inflammatory cytokines, including interleukin 1 beta (IL-1β) and tumor necrotic factor alpha (TNF-α) mRNA expressions, were determined using standard methods. Results: The leaf extract of T. Laurifolia decreased hepatic MDA levels, improved liver pathology and down-regulated mRNA expressions of CYP2E1, NADPH oxidase and pro-inflammatory cytokinesin ethanol-treated rats. Conclusion: These results demonstrate that aqueous extract of T. Laurifolia exerts hepatoprotective effect against alcoholic liver injury through a mechanism involving inhibition of oxidative stress and inflammation.Mahidol UniversityMedicineErratumSCOPUS10.4314/tjpr.v18i5.33