Rhea J. LongleyMichael T. WhiteJessica BrewsterZoe S.J. LiuCaitlin BourkeEizo TakashimaMatthias HarbersWai Hong ThamJulie HealerChetan E. ChitnisWuelton MonteiroMarcus LacerdaJetsumon SattabongkotTakafumi TsuboiIvo MuellerFaculty of Tropical Medicine, Mahidol UniversityWalter and Eliza Hall Institute of Medical ResearchUniversity of MelbourneFiocruz AmazôniaRikenUniversidade do Estado do AmazonasEhime UniversityInstitut Pasteur, ParisFundação de Medicina Tropical Dr. Heitor Vieira Dourado2022-08-042022-08-042021-06-01Open Forum Infectious Diseases. Vol.8, No.6 (2021)232889572-s2.0-85118669660https://repository.li.mahidol.ac.th/handle/20.500.14594/78128To achieve malaria elimination, new tools are required to explicitly target Plasmodium vivax. Recently, a novel panel of P. vivax proteins were identified and validated as serological markers for detecting recent exposure to P. vivax within the last 9 months. In order to improve the sensitivity and specificity of these markers, immunoglobulin M (IgM) in addition to immunoglobulin G (IgG) antibody responses were compared with a down-selected panel of 20 P. vivax proteins. IgM was tested using archival plasma samples from observational cohort studies conducted in malaria-endemic regions of Thailand and Brazil. IgM responses to these proteins generally had poorer classification performance than IgG.Mahidol UniversityMedicineArticleSCOPUS10.1093/ofid/ofab228