Chanchao LorthongpanichChuti LaowtammathronNittaya JiamvoraphongPimonwan SrisookPimjai ChingsuwanrotePhatchanat KlaihmonNattaya DamkhamPapussorn TerbtoSupaporn WaeteekulYaowalak U-pratyaSurapol IssaragrisilFaculty of Medicine, Siriraj Hospital, Mahidol UniversityWattanosoth Hospital2020-03-262020-03-262020-03-01Stem Cell Research. Vol.43, (2020)18767753187350612-s2.0-85078655191https://repository.li.mahidol.ac.th/handle/123456789/53574© 2020 The Author(s) Yes-associated protein (YAP) is an important transcriptional coactivator in the Hippo signaling pathway. Using CRISPR/Cas9 technology, we established a stable YAP-knockdown (YAP-KD) induced pluripotent stem cell (iPSC) from the MUSIi012-A cell line. The YAP-KD iPSC MUSIi012-A-2 maintained the pluripotent phenotype, the ability to differentiate into all three embryonic germ layers, and it maintained the normal karyotype.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyYAP-depleted iPSC MUSIi012-A-2 maintained all normal stem cell characteristicsArticleSCOPUS10.1016/j.scr.2020.101723