Suppamit DettrakulPrasat KittakoopMasahiko IsakaSombat NopichaiChotika SuyarnsestakornMorakot TanticharoenYodhathai ThebtaranonthMahidol UniversityThailand National Center for Genetic Engineering and Biotechnology2018-07-242018-07-242003-04-07Bioorganic and Medicinal Chemistry Letters. Vol.13, No.7 (2003), 1253-12550960894X2-s2.0-0037424702https://repository.li.mahidol.ac.th/handle/20.500.14594/20744Two new pimarane diterpenes, diaportheins A (1) and B (2), were isolated from a culture broth of the fungus Diaporthe sp. BCC 6140. Diaporthein B (2) strongly inhibited the growth of Mycobacterium tuberculosis with the MIC value of 3.1 μg/mL, while diaporthein A (1) showed only mild activity (MIC value of 200 μg/mL). © 2003 Elsevier Science Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1016/S0960-894X(03)00111-2