Pratoomrat TongkateWanchai PluempanupatWarinthorn ChavasiriMahidol University2018-07-122018-07-122008-02-11Tetrahedron Letters. Vol.49, No.7 (2008), 1146-1148004040392-s2.0-38349022154https://repository.li.mahidol.ac.th/handle/123456789/18970A new and efficient method for the bromination of alcohols utilizing Br3CCOCBr3/PPh3and Br3CCO2Et/PPh3is described. Various alcohols can be converted smoothly into their corresponding alkyl bromides in high yields under mild conditions with short reaction times. Based upon1H NMR studies using competitive reactions between selected brominating agents and Cl3CCN, Br3CCOCBr3displays the highest reactivity approximately nine times that of CBr4. © 2007 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1016/j.tetlet.2007.12.061