Visuthikosol T.Sirisopana K.Mahidol University2025-10-292025-10-292025-10-01Journal of the Medical Association of Thailand Vol.108 No.10 (2025) , 839-84401252208https://repository.li.mahidol.ac.th/handle/123456789/112803A single-port radical nephrectomy, in comparison to laparoscopic multiport and robot-assisted laparoscopic procedures, provides advantages such as a shorter recovery period, reduced postoperative pain, diminished blood loss, and satisfactory cosmetic results, despite a marginally extended operation duration. This paper presents a case involving renal cell carcinoma (RCC) in a native kidney of a patient who had undergone an ipsilateral kidney transplant. It illustrates an alternative treatment with a favorable safety profile and oncological outcomes. The patient chose to undergo this complex surgical procedure, thereby highlighting its feasibility and potential benefits in managing complex urological conditions.MedicineArticleSCOPUS10.35755/jmedassocthai.2025.10.839-844-022542-s2.0-105019368421