Phuriphong SongarjChutida SungworawongpanaNatchanan UhtsapunFaculty of Medicine, Siriraj Hospital, Mahidol University2019-08-232019-08-232018-09-01Journal of the Medical Association of Thailand. Vol.101, No.9 (2018), 133-142012522082-s2.0-85064228300https://repository.li.mahidol.ac.th/handle/123456789/46339© 2018, Medical Association of Thailand. All rights reserved. Objective: The present study aimed to determine the preferential technique of anesthesia, and compare the peri-procedure or treatment complications in acute ischemic stroke patients who received endovascular recanalization therapy. Materials and Methods: A retrospective descriptive cross-sectional study, data were collected from a list of patients who received endovascular recanalization therapy from January 2014 to December 2015. Data from all patients were retrieved from a database of the department of anesthesiology, Faculty of Medicine Siriraj Hospital. Baseline data were collected including age, sex, comorbidities, current medication, Glasgow Coma Scale [GCS] and stroke severity. Intra-procedural data and post-procedural complications were collected. Results: Ninety-one patients were enrolled to the present study, 86% received general anesthesia [GA]. All baseline patients’ characteristics were similar in both groups, except patients in local anesthesia [LA] group receiving anti-coagulants much more than GA group (p = 0.004). The overall procedure time and time record in stroke fast tract protocol were similar in both groups. In GA group found peri-procedural hypotension significantly greater than LA group (p<0.001). Hypertension and re-stroke were found in LA group, significantly greater than GA group (p = 0.034,p = 0.048). Conclusion: GA was more preferable technique than LA in patients undergoing endovascular recanalization therapy. LA provided less hypotension than GA during procedure. The patients receiving LA suffered from hypertension and re-stroke more than GA in post-procedural period. Both GA and LA did not show greater improvement in neurological status at 24 hours after treatment.Mahidol UniversityMedicineArticleSCOPUS