Baoliang CuiHeebyung ChaiThawatchai SantisukVichai ReutrakulNorman R. FarnsworthGeoffrey A. CordellJohn M. PezzutoA. Douglas KinghornUniversity of Illinois at ChicagoThe Forest Herbarium, Thailand Ministry of Natural Resources and EnvironmentMahidol University2018-07-042018-07-041997-12-29Tetrahedron. Vol.53, No.52 (1997), 17625-17632004040202-s2.0-0030712078https://repository.li.mahidol.ac.th/handle/20.500.14594/17875Bioassay-guided fractionation of the stems and fruits of Aglaia elliptica using human oral epidermoid carcinoma (KB) cells, led to the isolation of five cyclopenta[b]benzofurans, constituted by methyl rocaglate (1) and four novel compounds (2-5), along with three known dammarane triterpenoids. Compound 5 possesses an unusual formyl ester substituent at the C-1 position. The structures of the novel compounds were established on the basis of spectroscopic methods. Compounds 1-5 were found to be very potent cytotoxic substances when evaluated against a panel of human cancer cell lines.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1016/S0040-4020(97)10231-9