Kulkanya ChokephaibulkitNottasorn PlipatSutee YoksanWanatpreeya PhongsamartKeswadee LappraPimpanada ChearskulSanay ChearskulOrasri WittawatmongkolNirun VanpraparMahidol University2018-09-242018-09-242010-04-30Vaccine. Vol.28, No.20 (2010), 3563-35660264410X2-s2.0-77950689387https://repository.li.mahidol.ac.th/handle/20.500.14594/28729We report a prospective study of mouse brain derived inactivated Japanese encephalitis (JE) vaccine, given in 3-dose EPI program to human immune deficiency virus (HIV)-exposed Thai infants. 18 HIV-infected receiving antiretroviral therapy with median baseline CD4 of 33.1%, and 92 HIV-uninfected children were studied. All but one HIV-infected child seroconverted after the second dose. The geometric mean titers (GMTs) 3 months after the second and third doses in HIV-infected vs HIV-uninfected children were 247 vs 938 (p = 0.022), and 2273 vs 24069 (p = 0.009), respectively. Urticaria or angioedema found in 4% and 6% in HIV-infected and -uninfected children, respectively (p = 1.0). The vaccine was safe and immunogenic but antibody response in HIV-infected children was not as high as in uninfected children. © 2010 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicineArticleSCOPUS10.1016/j.vaccine.2010.02.108