Sakchai AuychaipornlertPojawon Prayurnprohm LawanprasertSuchada PiriyaprasarthPongtip SithisarnSilpakorn UniversityMahidol University2019-08-282019-08-282018-02-01ScienceAsia. Vol.44, No.1 (2018), 11-17151318742-s2.0-85048686979https://repository.li.mahidol.ac.th/handle/20.500.14594/47534© 2018 Science Society of Thailand under Royal Patronage. All rights reserved. The dried rhizome of turmeric (Curcuma longa) is a source of volatile oil and curcuminoids. Curcumin, the major component, has a wide spectrum of pharmacological activities. Various advanced techniques have been proposed to improve the efficacy of curcumin, especially nanoparticles formation techniques. In this study, we prepared turmeric spherical particles in an alcoholic water system to investigate their physicochemical properties. Turmeric spherical particles were in a nanometre size range with a narrow size distribution and negative surface charge. Additionally, we proposed an equation derived from the Young-Laplace equation which appears to be applicable to estimate an interfacial tension value of turmeric nanoparticles and other microemulsion systems.Mahidol UniversityMultidisciplinaryArticleSCOPUS10.2306/scienceasia1513-1874.2018.44.011