A. UngkanontW. MongkonsritrakoonS. JootarT. SrichaikulMahidol UniversityPramongkutklao HospitalVichaiyut Hospital2018-09-072018-09-072000-12-01Bone Marrow Transplantation. Vol.26, No.12 (2000), 1351-1354026833692-s2.0-0034486239https://repository.li.mahidol.ac.th/handle/20.500.14594/26094We have performed an allogeneic stem cell transplant in an 18-year-old male patient who had Burkitt's lymphoma. The patient had disease which was refractory to conventional intensive chemotherapy and radiation therapy. High-dose chemotherapy with autologous stem cell rescue was given but the patient relapsed within 2 months after transplantation. He was then treated with allogeneic stem cell transplantation using a fludarabine, busulfan and anti-thymocyte globulin-based conditioning regimen. His GVHD prophylaxis included mycophenolate and tacrolimus. The patient had engraftment within 14 days. Investigation by FISH showed more than 95% of his peripheral blood nucleated cells to be of donor origin since day +14. He is now alive and well and remains disease-free 6-months after the transplant. A graft-versus-lymphoma effect is thought to be one of the factors contributing to his remission.Mahidol UniversityMedicineAllogeneic stem cell transplantation in a patient with refractory Burkitt's lymphoma using non-myeloablative conditioning regimenArticleSCOPUS10.1038/sj.bmt.1702730