Sandip Kumar KhuranaAnju SehrawatRuchi TiwariMinakshi PrasadBaldev GulatiMuhammad Zubair ShabbirRajesh ChhabraKumaragurubaran KarthikShailesh Kumar PatelMamta PathakMohd Iqbal YatooVivek Kumar GuptaKuldeep DhamaRanjit SahWanpen ChaicumpaLala Lajpat Rai University of Veterinary and Animal SciencesICAR - Central Institute for Research on Buffaloes, HisarSKUAST-Kashmir, Faculty of Veterinary Sciences and Animal HusbandryTribhuvan University Teaching HospitalUniversity of Veterinary and Animal Sciences, LahoreTamilnadu Veterinary Animal Sciences UniversityCollege of Veterinary Science IndiaFaculty of Medicine Siriraj Hospital, Mahidol UniversityIndian Veterinary Research InstituteICAR-National Research Centre on Equine2022-08-042022-08-042021-01-01Veterinary Quarterly. Vol.41, No.1 (2021), 61-8818755941016521762-s2.0-85099708590https://repository.li.mahidol.ac.th/handle/123456789/79174Brucellosis is a zoonotic disease of great animal welfare and economic implications worldwide known since ancient times. The emergence of brucellosis in new areas as well as transmission of brucellosis from wild and domestic animals is of great significance in terms of new epidemiological dimensions. Brucellosis poses a major public health threat by the consumption of non-pasteurized milk and milk products produced by unhygienic dairy farms in endemic areas. Regular and meticulous surveillance is essentially required to determine the true picture of brucellosis especially in areas with continuous high prevalence. Additionally, international migration of humans, animals and trade of animal products has created a challenge for disease spread and diagnosis in non-endemic areas. Isolation and identification remain the gold standard test, which requires expertise. The advancement in diagnostic strategies coupled with screening of newly introduced animals is warranted to control the disease. Of note, the diagnostic value of miRNAs for appropriate detection of B. abortus infection has been shown. The most widely used vaccine strains to protect against Brucella infection and related abortions in cattle are strain 19 and RB51. Moreover, it is very important to note that no vaccine, which is highly protective, safe and effective is available either for bovines or human beings. Research results encourage the use of bacteriophage lysates in treatment of bovine brucellosis. One Health approach can aid in control of this disease, both in animals and man.Mahidol UniversityVeterinaryReviewSCOPUS10.1080/01652176.2020.1868616