Prapaporn NoparatayapornMontarat ThavorncharoensapUsa ChaikledkaewBhavani Shankara BagepallyAmmarin ThakkinstianSiriraj HospitalIndian Council of Medical ResearchFaculty of Medicine Ramathibodi Hospital, Mahidol UniversityMahidol University2022-08-042022-08-042021-07-01Obesity Surgery. Vol.31, No.7 (2021), 3279-329017080428096089232-s2.0-85105157464https://repository.li.mahidol.ac.th/handle/20.500.14594/78099This systematic review aimed to comprehensively synthesize cost-effectiveness evidences of bariatric surgery by pooling incremental net monetary benefits (INB). Twenty-eight full economic evaluation studies comparing bariatric surgery with usual care were identified from five databases. In high-income countries (HICs), bariatric surgery was cost-effective among mixed obesity group (i.e., obesity with/without diabetes) over a 10-year time horizon (pooled INB = $53,063.69; 95% CI $42,647.96, $63,479.43) and lifetime horizon (pooled INB = $101,897.96; 95% CI $79,390.93, $124,404.99). All studies conducted among obese with diabetes reported that bariatric surgery was cost-effective. Also, the pooled INB for obesity with diabetes group over lifetime horizon in HICs was $80,826.28 (95% CI $32,500.75, $129,151.81). Nevertheless, no evidence is available in low- and middle-income countries. Graphical abstract: [Figure not available: see fulltext.].Mahidol UniversityMedicineNursingReviewSCOPUS10.1007/s11695-021-05415-9