Nittaya TeerawattanasookDirek LimmathurotsakulNicholas P.J. DayVanaporn WuthiekanunNuffield Department of Clinical MedicineMahidol University2018-11-092018-11-092014-01-01American Journal of Tropical Medicine and Hygiene. Vol.91, No.6 (2014), 1173-1175000296372-s2.0-84918816394https://repository.li.mahidol.ac.th/handle/20.500.14594/34058Copyright © 2014 by The American Society of Tropical Medicine and Hygiene. We compared the organisms isolated from 30,210 pairs of blood culture bottles by using BacT/Alert system and the conventional system. Overall, 2,575 (8.5%) specimens were culture positive for pathogenic organisms. The sensitivity for detection of pathogenic organisms with the BACT/Alert system (85.6%, 2,203 of 2,575) was significantly higher than that with the conventional method (74.1%, 1,908 of 2,575; P < 0.0001). However, Burkholderia pseudomallei was isolated less often with the BacT/ALERT system (73.5%, 328 of 446) than with the conventional system (90.3%, 403 of 446; P < 0.0001). This finding suggests that use of the conventional culture method in conjunction with the BacT/Alert system may improve the isolation rate for B. pseudomallei in melioidosis-endemic areas.Mahidol UniversityImmunology and MicrobiologyMedicineArticleSCOPUS10.4269/ajtmh.14-0018