M. D. SmithV. WuthiekanunA. L. WalshN. J. WhiteMahidol UniversityNuffield Department of Clinical Medicine2018-07-042018-07-041996-04-29Journal of Antimicrobial Chemotherapy. Vol.37, No.3 (1996), 611-615030574532-s2.0-0029997403https://repository.li.mahidol.ac.th/handle/123456789/17744Four carbapenem antibiotics were tested for their in-vitro activities (MICs, MBCs and time-kill studies) against Burkholderia pseudomallei. The carbapenems were all more active than either ceftazidime or co-amoxiclav against strains of B. pseudomallei with a normal susceptibility pattern. Biapenem was the most active antibiotic tested. All four carbapenems retained bactericidal activity against 24 strains of B. pseudomallei with reduced susceptibility to ceftazidime and/or co-amoxiclav.Mahidol UniversityMedicinePharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1093/jac/37.3.611