Suravee SroymoraSumalee JindadamrongwechPunnee ButthepSuporn ChuncharuneeMahidol UniversityFaculty of Medicine, Ramathibodi Hospital, Mahidol University2018-06-112018-06-112012-06-01Hemoglobin. Vol.36, No.3 (2012), 293-2981532432X036302692-s2.0-84860786091https://repository.li.mahidol.ac.th/handle/20.500.14594/13709A rare nondeletional α-thalassemia-2 (α-thal-2) allele was identified in a Thai boy with Hb H (β4) disease. The proband has α-thal-1 (- SEA type) together with a non productive Hb Queens Park (HBA1:c.98T > A) [α32(B13)Met→Lys] α1-globin variant. No abnormal hemoglobin (Hb) fraction was detected by high performance liquid chromatography (HPLC). The clinical effect of this mutation in the proband was comparable to that of deletional α-thal-2 present in Hb H disease. Copyright © Informa Healthcare USA, Inc.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyMedicineArticleSCOPUS10.3109/03630269.2012.658939