Sanit ThongnestChulabhorn MahidolSomyote SutthivaiyakitSomsak RuchirawatChulabhorn Research InstituteThe Institute of Science and Technology for Research and Development, Mahidol UniversityRamkhamhaeng University2018-06-212018-06-212005-11-01Journal of Natural Products. Vol.68, No.11 (2005), 1632-1636016338642-s2.0-29044435162https://repository.li.mahidol.ac.th/handle/20.500.14594/16281Six new diterpenes, (1R,2S,5S,7S,9R,10S,13R)-1,2,7-trihydroxypimara-8(14), 15-diene (1), (1R,2S,5S,9S,10S,11R,13R)-1,2,11-trihydroxypimara-8(14),15-diene (2), (1S,5S,7R,9R,10S,11R,13R)-1,7,11-trihydroxypimara-8(14),15-diene (3), (1S,5S,9S,10S,11R,13R)-1,11-dihydroxypimara-8(14),15-diene (4), (5S,6R,9S,10S,13R)-6-hydroxypimara-8(14),15-diene-1-one (5), and (1R,2S,5S,7S,9R,10S,13R)-1,2-dihydroxypimara-8(14),15-diene-7-one (6), along with four known diterpenes, have been isolated from the dichloromethane extract of whole plants of Kaempferia marginata. The structures were assigned by spectroscopic methods. The absolute configuration of 1 was established by the Mosher ester method. Substances obtained were evaluated against a panel of bioassays including antimalarial, antituberculous, and antifungal activity. © 2005 American Chemical Society and American Society of Pharmacognosy.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryMedicinePharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1021/np050186l