Lertvipapath P.Taweechue A.J.Wongsa C.Thongngarm T.Uawattanasakul W.Sompornrattanaphan M.Mahidol University2025-11-162025-11-162025-09-01Asian Pacific Journal of Allergy and Immunology Vol.43 No.3 (2025) , 636-6390125877Xhttps://repository.li.mahidol.ac.th/handle/123456789/113020Background: Cutaneous manifestations of chronic spontaneous urticaria (CSU) are identical to type 1 hypersensitivity reactions. The daily occurrence of rash from occupational allergy could be misinterpreted as CSU exacerbation. Objective: We aim to report a nurse with concomitant CSU suffering from latex-induced anaphylaxis. Method: Skin tests, specific IgE using ImmunoCAP, and gloves challenge were performed. Result: A 27-year-old nurse with CSU suffered from several episodes of severe urticarial flare. H1-antihistamine up-dosing and oral corticosteroid burst were given. Unfortunately, she developed 3 episodes of anaphylaxis during her routine nursing care work on a medical ward, leading to allergist consultation. She had positive latex-specific IgE (6.86 kUA/L) and positive gloves challenge test. Conclusion: Concomitant CSU treatment might hinder the recognition of latex allergy by masking or delaying skin manifestations. IgE-mediated allergy should be suspected if there was a change in severity or frequency of previously controlled CSU or the presence of systemic symptoms.MedicineImmunology and MicrobiologyArticleSCOPUS10.12932/ap-050521-11262-s2.0-1050207022192228869434953476