Manu Pao-intaraChanan AngsuthanasombatSakol PanyimMahidol University2018-06-142018-06-141988-05-31Biochemical and Biophysical Research Communications. Vol.153, No.1 (1988), 294-300109021040006291X2-s2.0-0023914794https://repository.li.mahidol.ac.th/handle/123456789/15492Bacillus thuringiensis var. israelensis produces 130 kDa delta-endotoxin which is highly toxic to mosquito-larvae. The mosquito-larvicidal activity was delineated by sequential deletions from ends of the 1136 amino acids delta-endotoxin. A maximum of 459 amino acids could be removed from the carboxy-terminal of the toxin without a significant loss of the larvicidal activity. However, no more than 38 amino acids could be deleted from the amino-terminal without losing the toxicity. The truncated peptide of 72. kDa exhibited similar toxicity to the 130 kDa toxin and was between 39 th and 677 th amino acids. © 1988 Academic Press, Inc.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1016/S0006-291X(88)81221-X