Nongluck SookvanichsilpNoppamas SoonthornchareonnonNaun-anong Tad-ura2010-08-062011-08-292021-05-142010-08-062011-08-292021-05-142004Mahidol University Journal of Pharmaceutical Sciences. Vol. 31, No.3-4 (2004), 54-60.https://repository.li.mahidol.ac.th/handle/123456789/62182The root of white "Kwao Krua" has been used by Thai people as a rejuvenating folk medicine for a long period of time. The uterotropic activity and the TLC of the ethanolic and the dichloromethane extracts of white "Kwao Krua" roots from two sources, Pueraria cando/lei Benth. var. mirifica (Airy Shaw and Suvat) Niyomdham and Pueraria cando/lei Benth. var. cando/lei were determined and compared. In uterotropic assay, the ethanolic and the dichloromethane extracts at doses ranging uom 1 to 10 and 0.1 to 1 mg/kg'day, respectively, were given orally to immature female rats for 3 consecutive days. In TLC determination, the extracts were submitted to silica gel GF254 plates using two developing solvent systems, chloroform: methanol (8:2) and ethyl acetate: chloroform (6:4). The results revealed a higher uterotropic potency of the dichloromethane extract over the ethanolic extract, and the extracts of Pueraria cando/lei var. mirifica exhibited higher uterotropic activity than those ofPueraria cando/lei var. cando/lei. TLC chromatograms of the extracts of white "Kwao Krua" from two sources were similar. The bands of daidzein and genistein were more clearly seen on the dichloromethane chromatogram than on the et hanolic chromatogram of white "Kwao Krua" roots from both sources. @AII rights reserved.2724069 bytesapplication/pdfengMahidol UniversityKwao KruaPueraria candolleiPueraria mirificaTLCUterotropic activityArticle