Hosoya NorimasaResearch Foundation for Sugar MetabolismMahidol UniversityMeiji Seika Kaisha, Ltd.2018-06-142018-06-141988-01-01journal of clinical biochemistry and nutrition. Vol.5, No.1 (1988), 67-74091200092-s2.0-84996000137https://repository.li.mahidol.ac.th/handle/20.500.14594/15534Utilization of fructooligosaccharides, 1 F α-fructofura-nosyl) w n-1 -sucrose, which are not digestible in the small intestine but are fermentable by intestinal microorganisms in man, was investigated by a radiorespirometric study and an anaerobic incubation of [U- 14 C]fructooligosaccharides with feces. About 49% and 55% of the administered radioactivity were detected in expired 14 CO a after 24 and 48 h, respectively. In the anaerobic incubation, the saccharides were catabolized to 14 C0 2 (9.6%), microbial cell constituents (10.4%), and 14 C-volatile fatty acid (acetic acid, 24.1%; propionic acid, 20.2%; butyric acid, 11.4% and valeric acid, 2.2%). Complemental interpretation of the two studies allowed quantitation of the catabolic pathway of fructooligosaccharides in man, and utilization of the oligosaccharides was estimated to be 1.5 kcal/g. © 1988, SOCIETY FOR FREE RADICAL RESEARCH JAPAN. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyMedicineNursingArticleSCOPUS10.3164/jcbn.5.67