Robert W. SnowCarlos A. GuerraAbdisalan M. NoorHly Y. MyintSimon I. HayWellcome Trust Research Laboratories NairobiUniversity of OxfordMahidol University2018-06-212018-06-212005-09-07Nature. Vol.437, No.7056 (2005), E4-E5002808362-s2.0-84984770288https://repository.li.mahidol.ac.th/handle/20.500.14594/17203We have provided an evidence-based framework for estimating the public-health burden of P. falciparum malaria by using a uniform series of structured, transparent and reproducible data and methods to define the cartography of this parasite's clinical impact at a global scale. This contribution to global disease modelling is questioned by Nahlen et al. for United Nations agencies responsible for measuring development targets (see also ref. 3), and our estimation of the malaria burden outside Africa is challenged by Bell et al. © Nature Publishing Group.Mahidol UniversityMultidisciplinaryArticleSCOPUS10.1038/nature04180