Jin Yang BaekIn Ho ParkThomas Man kit SoM. K. LalithaNobuyuki ShimonoRohani Md YasinCelia C. CarlosJennifer PereraVisanu ThamlikitkulPo Ren HsuehPham Hung VanAtef M. ShiblJae Hoon SongKwan Soo KoAsia Pacific Foundation for Infectious Diseases (APFID)Ewha Womans UniversitySureCare Medical CentreMadras Medical MissionKyushu University, Faculty of Medical SciencesInstitute for Medical Research Kuala LumpurGokilaUniversity of ColomboMahidol UniversityNational Taiwan University HospitalUniversity of Medicine and PharmacyKing Saud UniversitySungKyunKwan University, School of Medicine2018-11-092018-11-092014-01-01Diagnostic Microbiology and Infectious Disease. Vol.80, No.4 (2014), 334-33718790070073288932-s2.0-84919355179https://repository.li.mahidol.ac.th/handle/20.500.14594/34848© 2014 Elsevier Inc. The prevalence, antimicrobial susceptibility, and genotypes of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries were investigated. A total of 244 S. pneumoniae serogroup 6 isolates obtained from 11 Asian countries were included in this study. Of the 244 serogroup 6 isolates, 101 (41.4%) were typed as "putative serotype 6E," followed by serotypes 6A, 6B, 6C, and 6D (27.0, 20.1, 5.7, and 5.7%, respectively). Multilocus sequence typing revealed that clonal complex (CC) 90, including ST90 and its variants, was the most prevalent clonal group of "putative serotype 6E" isolates (n = 63; 62.4%). CC146 and CC315 were also found frequently in some of the countries. Most of the "putative serotype 6E" isolates showed very high resistance rates against cefuroxime, erythromycin, azithromycin, clarithromycin, clindamycin, and trimethoprim/sulfamethoxazole, probably due to their highly resistant to antimicrobials clone, CC90. Our results indicate that "putative serotype 6E" is prevalent in Asian countries. The clonal dissemination of "putative serotype 6E" isolates was also identified.Mahidol UniversityMedicineArticleSCOPUS10.1016/j.diagmicrobio.2014.08.017