Laokulrath N.Chuwa E.Gudi M.Tan P.H.Mahidol University2024-12-162024-12-162024-12-01Pathobiology Vol.91 No.6 (2024) , 455-46210152008https://repository.li.mahidol.ac.th/handle/20.500.14594/102419Introduction: Diagnosing low-grade adenosquamous carcinoma (LGASC) presents significant challenges due to its subtle morphology, variable immunohistochemical expression, and resemblance to benign lesions like radial scar and complex sclerosing lesions. Case Presentation: We present a case of a 53-year-old woman with a subareolar mass initially thought to be a fibroepithelial neoplasm on core biopsy. Subsequent wide excision revealed LGASC with oestrogen receptor expression (weak to moderate intensity, 40% of tumour cells). Conclusion: These findings, rarely reported, highlight the difficulty of diagnosing LGASC on small tissue samples.Biochemistry, Genetics and Molecular BiologyMedicineArticleSCOPUS10.1159/0005400292-s2.0-852114479371423029138952139