Pattaraporn TustoTimothy E. O'BrienMontip TiensuwanMahidol UniversityLoyola University of ChicagoSouth Carolina Commission on Higher Education2018-12-112019-03-142018-12-112019-03-142016-04-13Model Assisted Statistics and Applications. Vol.11, No.2 (2016), 109-123157416992-s2.0-84965020930https://repository.li.mahidol.ac.th/handle/20.500.14594/40935© 2016 - IOS Press and the authors. All rights reserved. In this paper, we focus on the D- and Ds-optimal designs for two-parameter log-logistic (LL2) relative potency model where the response variables are normal and binomial distributions. The D- and Ds-optimal designs are obtained by using D-optimal design and nesting strategy criterions, respectively. Furthermore, the general equivalence theorems is used to guarantee the D- and Ds-optimal designs. The results show that we obtain four support points for D-optimal designs and two support points for Ds-optimal designs.Mahidol UniversityMathematicsArticleSCOPUS10.3233/MAS-150357