V. SaphonnU. VibolN. KumarasamyN. KurniatiS. M. FongN. K. Nik YusoffK. A. RazaliR. NallusamyV. SirisanthanaR. HansudewechakulP. LumbiganonJ. AnanworanichK. ChokephaibulkitH. K. TruongC. V. DoB. V. HuyA. H. SohnM. G. LawCleophas ChimbeteteBrian EleyDaniele GaroneJanet GiddyHarry MoultrieSam PhiriHans ProzeskyKarl TechnauPaula VazRobin WoodFrançois DabisEmmanuel BissagneneMarcel D. ZannouJoseph DraboSerge Paul EholieKevin PetersonLorna RennerMoussa MaigaMan CharuratHaby Signaté SyDidier K. EkouéviAntoine JaquetValériane LeroyCharlotte LewdenAnnette H. SohnNational Centre for HIV/AIDS Dermatology and STDsNational Pediatric HospitalGaitonde Centre for AIDS Research and EducationGeneral HospitalHospital LikasHospital Raja Perempuan Zainab IIKuala Lumpur HospitalPenang HospitalChiang Mai UniversityChiangrai Prachanukroh HospitalKhon Kaen UniversityThe HIV Netherlands Australia Thailand Research CollaborationMahidol UniversityChildren's Hospital 1Children's Hospital 2National Hospital of Pediatrics HanoiamfAR - The Foundation for AIDS ResearchUniversity of New South Wales (UNSW) AustraliaNewlands ClinicRed Cross War Memorial Children's HospitalKhayelitsha ART Programme and Médecins Sans FrontièresMcCord HospitalUniversity of WitwatersrandLighthouse ClinicTygerberg HospitalPaediatric Day HospitalDesmond Tutu HIV Centre (Gugulethu and Masiphumelele clinics)InsermCentre Hospitalier Universitaire de TreichvilleFoundation for AIDS Research2018-10-192018-10-192013-01-15Journal of the International AIDS Society. Vol.16, (2013)175826522-s2.0-84879590503https://repository.li.mahidol.ac.th/handle/20.500.14594/32573Introduction: There are limited data on paediatric HIV care and treatment programmes in low-resource settings. Methods: A standardized survey was completed by International epidemiologic Databases to Evaluate AIDS paediatric cohort sites in the regions of Asia-Pacific (AP), Central Africa (CA), East Africa (EA), Southern Africa (SA) and West Africa (WA) to understand operational resource availability and paediatric management practices. Data were collected through January 2010 using a secure, web-based software program (REDCap). Results: A total of 64,552 children were under care at 63 clinics (AP, N =10; CA, N =4; EA, N =29; SA, N =10; WA, N =10). Most were in urban settings (N =41, 65%) and received funding from governments (N =51, 81%), PEPFAR (N =34, 54%), and/or the Global Fund (N =15, 24%). The majority were combined adult-paediatric clinics (N =36, 57%). Prevention of mother-to-child transmission was integrated at 35 (56%) sites; 89% (N =56) had access to DNA PCR for infant diagnosis. African (N =40/53) but not Asian sites recommended exclusive breastfeeding up until 4-6 months. Regular laboratory monitoring included CD4 (N =60, 95%), and viral load (N =24, 38%). Although 42 (67%) sites had the ability to conduct acid-fast bacilli (AFB) smears, 23 (37%) sites could conduct AFB cultures and 18 (29%) sites could conduct tuberculosis drug susceptibility testing. Loss to follow-up was defined as >3 months of lost contact for 25 (40%) sites, >6 months for 27 sites (43%) and >12 months for 6 sites (10%). Telephone calls (N =52, 83%) and outreach worker home visits to trace children lost to follow-up (N =45, 71%) were common. Conclusions: In general, there was a high level of patient and laboratory monitoring within this multiregional paediatric cohort consortium that will facilitate detailed observational research studies. Practices will continue to be monitored as the WHO/UNAIDS Treatment 2.0 framework is implemented. © 2013 IeDEA Pediatric Working Group; licensee International AIDS Society.Mahidol UniversityMedicineArticleSCOPUS10.7448/IAS.16.1.17998