Kulvadee DolsophonJakapun SoponpongJittra KornsakulkarnChawanee ThongpanchangSamran PrabpaiPalangpon KongsaereeTienthong ThongpanchangMahidol UniversityThailand National Center for Genetic Engineering and Biotechnology2018-12-112019-03-142018-12-112019-03-142016-01-01Organic and Biomolecular Chemistry. Vol.14, No.46 (2016), 11002-11012147705202-s2.0-84998704813https://repository.li.mahidol.ac.th/handle/20.500.14594/43220© The Royal Society of Chemistry. F-THENA is designed as an alternative fluorine-containing chiral derivatizing agent (CDA). The fluorine atom functions exclusively as a reporter which can directly sense an anisotropic effect from an aromatic substituent of a chiral alcohol. In combination with chemical shift differences from both19F NMR and1H NMR, the F-THENA method can successfully be used for determining the absolute configuration of chiral secondary aromatic alcohols with a self-validating system.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryArticleSCOPUS10.1039/C6OB02255C