Noppamas SoonthornchareonnonMonnun SakayarojkulMasahiko IsakaVanna MahakittikunWongsatit ChuakulPrapai WongsinkongmanMahidol UniversityThailand National Center for Genetic Engineering and BiotechnologyThailand Ministry of Public Health2018-06-212018-06-212005-02-01Chemical and Pharmaceutical Bulletin. Vol.53, No.2 (2005), 241-243000923632-s2.0-19444380411https://repository.li.mahidol.ac.th/handle/20.500.14594/16454A new daphnane diterpenoid, rediocide F (1), was isolated together with three known compounds, rediocides A (2), C (3) and E (4), from the hexane extract of Trigonostemon reidioides roots by bioassay-guided fractionation for acaricidal activity on Dermatophagoides pteronyssinus, Thai common house dust mite. The structure of rediocide F (1) was established as the demethyl analog of rediocide C (3) on the basis of spectral analysis. Compounds 1-4 exhibited potent activity against D. pteronyssinus with respective LC50 values of 2.53, 0.78, 5.59 and 0.92 μg/cm2. © 2005 Pharmaceutical Society of Japan.Mahidol UniversityChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1248/cpb.53.241