Ratchanok PingaewSupaluk PrachayasittikulSomsak RuchirawatVirapong PrachayasittikulSrinakharinwirot UniversityMahidol UniversityChulabhorn Research InstituteCenter of Excellence on Environmental Health2018-10-192018-10-192013-10-01Chinese Chemical Letters. Vol.24, No.10 (2013), 941-944100184172-s2.0-84883739431https://repository.li.mahidol.ac.th/handle/20.500.14594/31511An operationally simple and eco-friendly protocol has been developed for the synthesis of N-sulfonyl-1,2,3,4-tetrahydroisoquinolines 3 using the modified Pictet-Spengler reaction of N-sulfonylphenylethylamines 1 and various aldehydes 2 in the presence of tungstophosphoric acid hydrate. © 2013 Zhi-Jin Fan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.Mahidol UniversityChemistryArticleSCOPUS10.1016/j.cclet.2013.06.019