Ronnarong PalasoonSasiporn PanasophonkulPrapee SretarugsaPeter HannaPrasert SobhonJittipan ChavadejMahidol UniversityRangsit UniversityDeakin University2018-05-032018-05-032011-06-01Invertebrate Neuroscience. Vol.11, No.1 (2011), 29-42135425162-s2.0-80052464288https://repository.li.mahidol.ac.th/handle/20.500.14594/12786Immunohistochemistry was used to identify the distribution of both APGWamide-like and RFamide-like peptides in the central nervous system (CNS) and ovary of the mature female giant freshwater prawn, Macrobrachium rosenbergii. APGWamide-like immunoreactivity (ALP-ir) was found only within the sinus gland (SG) of the eyestalk, in small- and medium-sized neurons of cluster 4, as well as their varicosed axons. RFamide-like immunoreactivity (RF-ir) was detected in neurons of all neuronal clusters of the eyestalk and CNS, except clusters 1 and 5 of the eyestalk, and dorsal clusters of the subesophageal, thoracic, and abdominal ganglia. The RF-ir was also found in all neuropils of the CNS and SG, except the lamina ganglionaris. These immunohistochemical locations of the APGWamidelike and RF-like peptides in the eyestalk indicate that these neuropeptides could modulate the release of the neurohormones in the sinus gland. The presence of RFamide-like peptides in the thoracic and abdominal ganglia suggests that it may act as a neurotransmitter which controls muscular contractions. In the ovary, RF-ir was found predominantly in lateprevitellogenic and early vitellogenic oocytes, and to a lesser degree in late vitellogenic oocytes. These RFs may be involved with oocyte development, but may also act with other neurohormones and/or neurotransmitters within the oocyte in an autocrine or paracrine manner. © Springer-Verlag 2011.Mahidol UniversityNeuroscienceArticleSCOPUS10.1007/s10158-011-0115-4