Rosli Mohd AliRalf DegenhardtRobaayah ZambahariDamras TresukosolWan Azman Wan AhmadHaizal Bin Haron KamarSim Kui-HianTiong Kiam OngOmar Bin IsmailSafari Bin ElisWasan UdychalermHanns AckermannMichael BoxbergerMartin UnverdorbenInstitut Jantung Negara Kuala LumpurCenter for Cardiovascular DiseasesMahidol UniversityUniversity of Malaya Medical CentreSarawak HospitalPenang HospitalKing Chulalongkorn Memorial Hospital, Faculty of Medicine Chulalongkorn UniversityGoethe-Universitat Frankfurt am MainVascular SystemB. Braun Medical Inc.2018-05-032018-05-032011-05-01EuroIntervention. Vol.7, No.SUPPL. K (2011)196962131774024X2-s2.0-80155154054https://repository.li.mahidol.ac.th/handle/20.500.14594/12532Aims: Coronary lesions in diabetics (DM) are associated with a high recurrence following percutaneous coronary intervention (PCI), even after drug-eluting stent (DES) deployment. Encouraging clinical data of the drug-eluting balloon catheter (DEB) SeQuent Please warrant its investigation in these patients. Methods and results: Eighty-four diabetic patients (60.8±9.1years, 76.2% male) were randomised to either the DEB SeQuent™ Please or the DES Taxus™ Liberte™ to compare the 9-month clinical and angiographic outcome of PCI in native coronary arteries. Comparing the DEB vs. the DES the 9-month results (follow-up DEB 39/45 [86.7%], DES 36/39 [92.3%] ) are statistically not different at the 0.05 level for the primary end- point of in-segment (0.37±0.59 mm vs. 0.35 ±0.63 mm) and in-stent (0.51±0.61 mm vs. 0.53±0.67 mm) late lumen loss, overall and cardiac deaths (2/45 [4.4%] and 3/45 [6.7%] vs. 0), target lesion revascularisation (3/45 [8.9%] vs. 4/39 [10.3%] ), the total MACE rate (6/45 [13.3%] vs. 6/39 [15.4%] ), and the event free survival after 10.2±3.8 months (Kaplan-Meier analysis, p < 0.80, log rank test). Conclusions: The clinical and angiographic outcome of the combination of the drug-eluting balloon SeQuent Please with a cobalt chromium stent compared to the drug eluting Taxus stent are similar. © Europa Edition 2011. All rights reserved.Mahidol UniversityMedicineArticleSCOPUS10.4244/EIJV7SKA15