Weerachai NasomphanPramuan TangboriboonratSutipa TanapongpipatSrung SmanmooThailand National Center for Genetic Engineering and BiotechnologyMahidol University2018-11-092018-11-092014-01-01Journal of Fluorescence. Vol.24, No.1 (2014), 7-11105305092-s2.0-84894592972https://repository.li.mahidol.ac.th/handle/20.500.14594/33375Highly water soluble polymer (DD) was prepared and evaluated for its fluorescence response towards various amino acids. The polymer consists of dansyl hydrazine unit conjugated into dextran template. The conjugation enhances higher water solubility of dansyl hydrazine moiety. Of screened amino acids, DD exhibited selective fluorescence quenching in the presence of aspartic acid (Asp) and glutamic acid (Glu). A plot of fluorescence intensity change of DD against the concentration of corresponding amino acids gave a good linear relationship in the range of 1 × 10-4M to 25 × 10-3M. This establishes DD as a potential polymeric sensor for selective sensing of Asp and Glu. [Figure not available: see fulltext.] © 2013 Springer Science+Business Media New York.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryArticleSCOPUS10.1007/s10895-013-1269-8