Preeyachan LourthaiPitipol ChoopongDhanach DhirachaikulpanichKunravitch SoraprajumWarinyupa PinitpuwadolNoppakhun PunyayingyongYaninsiri NgathaweesukNattaporn TesavibulSutasinee BoonsoponSiriraj HospitalMettapracharak Hospital, Nakhon PathomPhramongkutklao College of Medicine2022-08-042022-08-042021-12-01Scientific Reports. Vol.11, No.1 (2021)204523222-s2.0-85110502351https://repository.li.mahidol.ac.th/handle/20.500.14594/79228To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agents were predominantly gram-negative bacteria (48.1%). The most common specie was Klebsiella pneumoniae (25.9%). About a quarter of the patients required surgical eye removal, and the remaining 45.7% had visual acuity (VA) worse than hand motion at one month after the infectious episode. The most common complication was ocular hypertension (52.5%). Poor initial VA was significantly associated with a worse visual outcome in the early post-treatment period (p 0.12, adjusted OR 10.20, 95% CI 1.65–62.96). Five patients continued to visit the clinic for at least ten years. One patient had gained his vision from hand motion to 6/7.5. Two patients had visual deterioration, one from corneal decompensation, and the other from chronic retinal re-detachment. Two patients developed phthisis bulbi, with either some VA perception of light or no light perception. Poor initial VA is the only prognostic factor of a poor early post-treatment visual outcome of EE.Mahidol UniversityMultidisciplinaryArticleSCOPUS10.1038/s41598-021-93730-7