Somyote SutthivaiyakitWantana MongkolvisutSamran PrabpaiPalangpon KongsaereeRamkhamhaeng UniversityRajamangala University of Technology systemMahidol University2018-09-132018-09-132009-11-30Journal of Natural Products. Vol.72, No.11 (2009), 2024-2027016338642-s2.0-73349140850https://repository.li.mahidol.ac.th/handle/20.500.14594/27113Five new compounds, 2α-hydroxyjatropholone (1), 2β- hydroxyjatropholone (2), 1,5-dioxo-2,3-dihydroxyrhamnofola-4(10),6,11(18),15- tetraene (3), 2-keto-5-hydroxyguai-3,11-diene (4), and a sesquiterpene - coumarin conjugate, jatrophadioxan (5), and nine known compounds have been isolated from the roots of Jatropha integerrima. The structures were established from spectroscopic data, and the relative configuration of 1 was confirmed by X-ray crystallography. Six diterpenes were evaluated for their antiplasmodial, antituberculosis, and cytotoxic activities. © 2009 American Chemical Society and American Society of Pharmacognosy.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryMedicinePharmacology, Toxicology and PharmaceuticsNoteSCOPUS10.1021/np900342b