Supakanya WongrakpanichAmaraporn WongrakpanichKatie MelhadoJanani RangaswamiMahidol University2019-08-232019-08-232018-02-01Aging and Disease. Vol.9, No.1 (2018), 143-150215252502-s2.0-85043705728https://repository.li.mahidol.ac.th/handle/20.500.14594/45253© 2017 Wongrakpanich S et al. NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID induced nephrotoxicity. As our society ages, it is crucial to have comprehensive knowledge of this class of medication in the elderly population. Therefore, we reviewed the pharmacodynamics and pharmacokinetics, current guidelines for NSAIDs use, adverse effect profile, and drug interaction of NSAIDs and commonly used medications in the elderly.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyMedicineReviewSCOPUS10.14336/AD.2017.0306