Putipun Puataweepongพุฒิพรรณ พัวทวีพงศ์Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Diagnostic and Therapeutic Radiology2022-10-112022-10-112022-10-112009Ramathibodi Medical Journal. Vol. 32, No. 1 (Jan-Mar 2009), 43-500125-3611 (Print)2651-0561 (Online)https://repository.li.mahidol.ac.th/handle/20.500.14594/79885Stereotactic radiosurgery is a non-invasive procedure that utilizes precisely targeted radiation as an ablative surgical tool. Conventional radiosurgery devices, such as the Gamma Knife and X-Knife rely upon skeletally attached stereotactic frames to immobilize the patient and precisely determine the 3D spatial position of a tumor. A relatively new instrument, the CyberKnife (Accuray, Inc., Sunnyvale, CA), makes it possible to administer radiosurgery without a frame. The CyberKnife localizes clinical targets using a very accurate Image-to-Image correlation algorithm, and precisely cross-fires high-energy radiation from a lightweight linear accelerator by means of a highly manipulable robotic arm, Cyberknife radiosurgery is an effective alternative to conventional surgery or radiation therapy for a range of tumors and some non-neoplastic disorders. This report will describe Cyberknife technology and oncologic applications in neurosurgery and throughout the body.engMahidol UniversityRadiosurgeryCyberKnife Imaged-guidedTumor ablationStereotacticReview ArticleDepartment of Diagnostic and Therapeutic Radiology Faculty of Medicine Ramathibodi Hospital Mahidol University