Witoon Youngsa-adNattaya NgamrojanavanichChulabhorn MahidolSomsak RuchirawatHunsa PrawatPrasat KittakoopChulabhorn Research InstituteChulalongkorn UniversityChulabhorn Graduate InstituteThe Institute of Science and Technology for Research and Development, Mahidol University2018-08-242018-08-242007-11-01Planta Medica. Vol.73, No.14 (2007), 1491-1494003209432-s2.0-36949003723https://repository.li.mahidol.ac.th/handle/20.500.14594/23969Two new clerodane diterpenes, methyl 15,16-epoxy-3,13(16),14-ent- clerodatrien-18,19-olide-17-carboxylate (1) and dimethyl 15,16-epoxy-12-oxo-3, 13(16),14-ent-clerodatriene-17,18-dicarboxylate (2), together with seven known compounds (3-9), were isolated from the roots of Croton oblongifolius. The isolated compounds showed only mild cytotoxic activity against HuCCA-1, KB, HeLa, MDA-MB231, and T47D cell lines with IC50 values ranging from 10 to 50 μg/mL. © Georg Thieme Verlag KG Stuttgart.Mahidol UniversityAgricultural and Biological SciencesChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1055/s-2007-990247