Bajracharya A.R.Seng-Iad S.Sasaki K.Guerra G.Mahidol University2023-11-052023-11-052023-01-01Canadian Prosthetics and Orthotics Journal Vol.6 No.1 (2023)https://repository.li.mahidol.ac.th/handle/20.500.14594/90945BACKGROUND: Objective mobility measurement of Nepali prosthesis users is lacking. OBJECTIVE: The objective of this study was to cross-culturally adapt, translate and evaluate construct validity of the Prosthetic Limb Users Survey of Mobility (PLUS-M™/Nepali-12 Short Form (SF)) instrument in lower limb prosthesis users residing in Nepal. METHODOLOGY: Two forward translations, review and reconciliation, back translation, expert review, developer review to create the PLUS-M™/Nepali-12SF. Psychometric testing for internal consistency, test-retest reliability and construct validity against the Two-Minute Walk Test (2MWT) and Amputee Mobility Predictor with Prosthesis (AMPPRO) were performed on sixty-six lower limb prosthesis users. FINDINGS: The majority of populations were with transtibial amputation 45 (68%), with transfemoral amputation 15 (23%), with knee disarticulation 5 (7.5%) and with syme’s amputation 1 (1.5%). The most common cause of amputation among the population was trauma and the least was tumor. Chronbach’s alpha for the PLUS-M™/Nepali-12SF was 0.90, mean T-Score was 52.90, test-retest intraclass correlation coefficient (ICC) was 0.94 (95% confidence interval 0.90-0.96). Construct validity with the 2MWT was good (r = 0.62, p< 0.001) and moderately positive with the AMPPRO (r = 0.57, p< 0.001). CONCLUSION: Our research evidenced that the PLUS-M™/Nepali -12SF had excellent reproducibility. The significance of this work is that it may allow for the measurement of mobility in austere locations of Nepal.MedicineCROSS-CULTURAL ADAPTATION AND VALIDATION OF THE NEPALI VERSION OF THE PROSTHETIC LIMB USERS SURVEY OF MOBILITY SHORT-FORM (PLUS-M<sup>™</sup>/NEPALI-12SF) IN LOWER LIMB PROSTHESIS USERSArticleSCOPUS10.33137/cpoj.v6i1.413102-s2.0-851750557372561987X