Synthesis of (+)-lentiginosine and its pyrrolizidine analogue based on intramolecular cyclization of α-sulfinyl carbanions

Sakkarin Du-A-ManDarunee SoorukramChutima KuhakarnPatoomratana TuchindaVichai ReutrakulManat PohmakotrMahidol University2018-11-092018-11-092014-03-01European Journal of Organic Chemistry. Vol.2014, No.8 (2014), 1708-1715109906901434193X2-s2.0-84897628501https://repository.li.mahidol.ac.th/handle/20.500.14594/33628A synthesis of (+)-lentiginosine and its pyrrolizidine analogue was accomplished in six steps, starting from L-(+)-tartaric acid. The key step of these syntheses involves the intramolecular cyclization of α-sulfinyl carbanions for the construction of the indolizidine or pyrrolizidine ring. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Mahidol UniversityChemistrySynthesis of (+)-lentiginosine and its pyrrolizidine analogue based on intramolecular cyclization of α-sulfinyl carbanionsArticleSCOPUS10.1002/ejoc.201301671