Kanyanat MeejaroenCharoen ChaweechanWanus KhodsiriVorapranee Khu-SmithUkrit WatchareeruetaiPattana SornmaguraTaya KittiyakaraKing Mongkut's Institute of Technology LadkrabangMahidol University2018-11-232018-11-232015-01-01Proceedings of the 2015-7th International Conference on Knowledge and Smart Technology, KST 2015. (2015), 184-1892-s2.0-84925857633https://repository.li.mahidol.ac.th/handle/20.500.14594/35847© 2015 IEEE. In this paper, an image-processing-based method designed to detect fibrosis in liver biopsy images is proposed. The proposed method first enhances the color difference between liver tissue and fibrosis areas. Then, a low-pass filtering is applied to each color band to reduce noise. In order to calculate the percentage of fibrosis against total liver tissue, the background area, i.e. empty slide area, is detected. Next, Bayesian classifier is used to separate fibrosis from liver tissue based on the color information. Finally, the proportion of the fibrosis area to the tissue area is computed. Experimental results show that the proposed method can estimate and detect fibrosis in the liver biopsy images with the classification accuracy of 91.42%. In addition, the average difference between the percentage of fibrosis obtained from the proposed method and that in ground truth images is 2.29 points.Mahidol UniversityComputer ScienceConference PaperSCOPUS10.1109/KST.2015.7051484