Chi Cheng LaiKyungwon LeeYonghong XiaoNorazah AhmadBalaji VeeraraghavanVisanu ThamlikitkulPaul Ananth TambyahR. H.H. NelwanAtef M. ShiblJiunn Jong WuWing Hong SetoPo Ren HsuehChi Mei Medical CenterYonsei University College of MedicineZhejiang UniversityInstitute for Medical Research Kuala LumpurChristian Medical College, VelloreMahidol UniversityNational University Hospital, SingaporeUniversity of Indonesia, RSUPN Dr. Cipto MangunkusumoKing Saud UniversityNational Cheng Kung UniversityHong Kong Hospital AuthorityNational Taiwan University Hospital2018-11-092018-11-092014-01-01Journal of Global Antimicrobial Resistance. Vol.2, No.3 (2014), 141-14722137173221371652-s2.0-84906791359https://repository.li.mahidol.ac.th/handle/20.500.14594/34110The rapid development of antimicrobial resistance among micro-organisms is a serious public health concern. Moreover, the dissemination of antibiotic-resistant bacteria makes this issue a global problem, and Asia is no exception. For example, since New Delhi metallo-β-lactamase (NDM)-producing Enterobacteriaceae were identified in India, further spread of NDM has become a worldwide threat. However, the epidemiology of antibiotic-resistant bacteria in Asia may be different to other regions, and clinical condition may be worse than in western countries. Antibiotic-resistant bacteria, including community-acquired and hospital-acquired meticillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate S. aureus (VISA), vancomycin-resistant enterococci, macrolide- and penicillin-resistant Streptococcus pneumoniae, extend-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa and Acinetobacter spp., are becoming prevalent in many countries in Asia. Moreover, the prevalence of each antibiotic-resistant bacterium in each country is not identical. This review provides useful information regarding the critical condition of antibiotic resistance in Asia and emphasises the importance of continuous surveillance of resistance data. © 2014 International Society for Chemotherapy of Infection and Cancer.Mahidol UniversityImmunology and MicrobiologyMedicineHigh burden of antimicrobial drug resistance in AsiaReviewSCOPUS10.1016/j.jgar.2014.02.007