Oxidative conversion of amines into their corresponding nitriles using o-iodoxybenzoic acid (IBX)/iodine: Selective oxidation of aminoalcohols to hydroxynitriles

Supanimit ChiampanichayakulManat PohmakotrVichai ReutrakulThaworn JaipetchChutima KuhakarnMahidol University2018-07-122018-07-122008-07-01Synthesis. No.13 (2008), 2045-2048003978812-s2.0-47349117719https://repository.li.mahidol.ac.th/handle/123456789/19040o-Iodoxybenzoic acid (IBX)/iodine in dimethyl sulfoxide at 65 °C oxidatively and efficiently converted various amines into the corresponding nitriles in good to excellent yields. Under the reaction conditions, amines were selectively oxidized to the nitrile in the presence of a primary hydroxy group within the same molecule. © Thieme Stuttgart.Mahidol UniversityChemical EngineeringChemistryOxidative conversion of amines into their corresponding nitriles using o-iodoxybenzoic acid (IBX)/iodine: Selective oxidation of aminoalcohols to hydroxynitrilesArticleSCOPUS10.1055/s-2008-1067123