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Recent Submissions
Perceptions of Campus Climate on LGBTQ+ Students’ Inclusion in Thai Higher Education
(2026-03-12) Doungphummes N.; Rodyim M.; Siwapathomchai S.; Aydin H.; Doungphummes N.; Mahidol University
This study examines the perceptions of campus atmosphere among LGBTQ+ students in Thai higher education, investigating the interplay of regional, academic, and identity-related factors that influence student experiences. The study employed a quantitative research approach to poll 688 students from multiple Thai colleges, encompassing both LGBTQ+ and heterosexual individuals. The data indicates that, although the general campus climate is viewed favorably, notable geographical and disciplinary disparities are present. LGBTQ+ students from southern regions expressed less favorable opinions, indicative of regional cultural and religious conservatism. Moreover, although both LGBTQ+ and heterosexual students typically indicated feeling respected, LGBTQ+ students assessed the climate as slightly more inclusive, emphasizing the significance of peer relationships and visibility in cultivating a supportive atmosphere. Gender identification exerted a negligible influence on perceptions of safety and inclusion; however, transgender students indicated somewhat reduced levels of comfort. The study highlighted the importance of intersectionality in understanding campus climate, illustrating how intersecting identities—such as gender, sexual orientation, and regional background—influence students' sense of inclusion. These findings contribute to the broader discussion on LGBTQ+ inclusion in higher education by questioning the notion of universal progress and promoting region-specific, culturally relevant solutions. The study's findings necessitate a heightened institutional focus on regional inequities, LGBTQ+ representation, and peer engagement to foster genuinely inclusive academic environments for all students.
Correlation between clinical disease activity and interferon-γ autoantibody titers measured by inhibitory ELISA, and inflammatory biomarkers in adult-onset immunodeficiency associated with anti-interferon-γ autoantibodies
(2026-03-01) Teepapan P.; Chungcharoenpanich A.; Pinyopornpanish K.; Oncham S.; Chantharit P.; Rotjanapan P.; Laisuan W.; Teepapan P.; Mahidol University
Background Anti-interferon-γ autoantibodies (Anti-IFN-γ AAbs) contribute to immunodeficiency and increase susceptibility to intracellular infections, particularly in adults. Measurement of anti-IFN-γ AAb titers using inhibitory ELISA is a valuable diagnostic tool for adult-onset immunodeficiency. However, the relationship between inhibitory ELISA titers, inflammatory biomarkers, and clinical disease activity remains unclear. Methods This retrospective study analyzed 69 blood samples from 39 patients with detectable anti-IFN-γ AAbs at Ramathibodi Hospital. Data collected included demographics, clinical disease activity, and laboratory biomarkers such as white blood cell (WBC) count, interleukin-6 (IL-6), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and inhibitory ELISA titers. Disease activity was categorized as active or in remission based on clinical evaluation and the status of infection. Results The mean patient age was 58.38 ± 8.55 years, and 61.5% were female. Anti-IFN-γ AAb titers had an area under the receiver operating characteristic curve (AUC) of 0.893. A cut-off of 1:50,000 (50% inhibition) yielded 92.90% specificity in determining active disease status. Median titers were significantly higher in active disease (1:100,000, interquartile range [IQR]: 1:10,000–1:100,000) compared with remission (1:5,000, IQR: 1:5,000–1:10,000, p<0.001). Combining anti-IFN-γ AAb titers (≥ 1:50,000) with ESR (≥ 45 mm/hr), CRP (≥ 18 mg/dL), WBC (≥ 10,455 cells/µL), and IL-6 (≥ 16 pg/mL) further improved the prediction of disease activity (AUC=0.903, sensitivity=88.9%, specificity=91.7%). Conclusions High anti-IFN-γ AAb titers correlate with active disease, and inhibitory ELISA may aid in disease monitoring. Combining IFN-γ AAbs titers with inflammatory biomarkers may improve predictive accuracy.
Re-constructing “Chineseness” in the Frontiers of Statehood, Memory, and Territory: The Kuomintang Communities of Northern Thailand
(2025-01-01) Ohlendorf H.; Ohlendorf H.; Mahidol University
Diasporic identity is not merely inherited, but is actively constructed through memory, heritage, and negotiation with shifting geopolitical forces. Yet, little attention has been paid to how communities at the margins of statehood reimagine belonging through cultural memory. This study addresses that gap by examining a distinct Kuomintang diaspora community in Northern Thailand, where such identity work is particularly visible. It discusses the reconstruction of “Chineseness” in the small village of Mae Salong, which was founded by Chinese Kuomintang (KMT) soldiers fleeing the Chinese Civil War. The article examines how geopolitical events, cross-border migration, and memory have shaped this community’s identity at the frontiers of statehood and territory. Using theories of collective and cultural memory, the article analyzes key sites of memory, including the Chinese Martyrs’ Memorial and General Xi Duanwen’s tomb, to show how these communities have utilized memory and heritage to carve out new spaces of identity and belonging. The role of tourism in influencing these memory constructions is also emphasized, with a focus on how local traditions are displayed to meet tourists’ expectations. By analyzing how historical narratives and cultural practices are preserved, adapted, and reimagined in Mae Salong, this article offers insights into the broader dynamics of identity formation in Chinese diaspora communities.
THE SECOND RECORD OF A FIRETHROAT CALLIOPE PECTARDENS IN THAILAND
(2024-01-01) Round P.; Jearwattanakanok A.; Walser-Schwyzer P.; Khudamrongsawat J.; Round P.; Mahidol University
The second record of an apparently over-wintering Firethroat Calliope pectardens (Muscicapidae) in northern Thailand, a female, caught and ringed following its discovery, is documented. Reference is made to a previous Thai record of the Firethroat’s sister species, the Blackthroat C. obscura. Since the females of both species are very similar, the identity of the present individual was confirmed both by examination in the hand and by DNA assay. The importance of maintaining marginal lowland habitats, such as scrub and reeds along the banks of lowland watercourses and around field margins, so as to maintain biodiversity in intensively agricultural lowland landscapes, is discussed.
Molecular landscape of prostate cancers with clival metastases
(2026-04-01) Likasitwatanakul P.; Blinka S.M.; Zarka J.G.; Gebrael G.; Weg E.; Longoria O.; Moore J.A.; Sharp A.; De Bono J.; Sternberg C.N.; Agarwal N.; Swami U.; Orme J.J.; Schweizer M.T.; Sloan L.; Hwang J.H.; Antonarakis E.S.; Likasitwatanakul P.; Mahidol University
Background Clival metastases are a rare and clinically aggressive manifestation of advanced prostate cancer, associated with cranial nerve palsy and poor survival. The molecular features of prostate cancers giving rise to clivus metastases remain unknown. Patients and methods We performed a multi-center retrospective study across six institutions, identifying prostate cancer patients with radiographically confirmed clival metastases and available next-generation sequencing (NGS) data. Baseline characteristics and clinical outcomes were collected. Genomic alterations from tissue- and/or blood-based assays were aggregated at the patient level and compared with a publicly available metastatic castration-resistant prostate cancer (mCRPC) cohort (SU2C/PCF). Results Fifty-nine patients with clival metastases contributed 87 molecular assays. More than half of patients had Gleason grade group 5 cancer and presented with de novo metastatic (M1) disease. The median interval from initial prostate cancer diagnosis to clival metastasis was 71.4 months (95% CI, 42.0-101.7), while median overall survival following clival involvement was only 15.3 months (95% CI, 6.9-22.8). Compared with the SU2C/PCF mCRPC cohort, clival metastases showed significant enrichment of BRAF and CHEK2 alterations as well as homologous recombination repair (HRR) with relative depletion of AR-related, PI3K pathway, and G2–M pathway alterations. Conclusion Prostate cancers giving rise to clival metastases exhibit a distinct molecular profile enriched for DNA damage–repair and RAF kinase alterations, suggesting unique metastatic biology and potential therapeutic vulnerabilities.