Mahidol University's Institutional Repository
คลังสารสนเทศสถาบันของมหาวิทยาลัยมหิดล
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To collect Mahidol University's academic publications and intellectual properties more than 39 faculties
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Recent Submissions
Development of Web Application to Support Dengue Investigation Team of Communicable Disease Control Operations Unit in Phang Nga Province
(2025) Suwadee Kongpan; Pichitpong Soontornpipit; Jutatip Sillabutra; Prasong Kitidamrongsuk; Pratana Satitvipawee; Vanvisa Sresumatchai
Phang Nga Province in Thailand continues to face persistent challenges related to Dengue Hemorrhagic Fever (DHF) and associated fatalities. In response to the limitations of existing paper-based systems in managing dengue fever data effectively, this study aims to develop a web application to support the Dengue Investigation Team within the Communicable Disease Control Operations Unit in Phang Nga Province. The research engaged 22 stakeholders, including public health officers, data managers, and field investigators, who participated in a stakeholder analysis process to identify user requirements that would inform the design and development phases.Utilizing Agile Software Development Lifecycle (SDLC) methodologies, the web application was developed using MySQL for database management and PHP for web service programming. The resulting web application includes functionalities for data collection and a stakeholder dashboard for statistical analysis. Testing and evaluation were conducted using satisfaction scales, which yielded high satisfaction scores (mean ± SD) across functionality, usability, and accessibility. Stakeholder feedback indicated the need for additional features to enhance data collection, analysis, and integration of information across healthcare facilities.
The evaluation results highlight the application's potential to address public health challenges and support the Dengue Investigation Team in combatting dengue fever in the region. Currently, the application is in the pilot testing phase, and further refinement is necessary to improve data integration and security measures. This research contributes to advancing disease surveillance and control measures, emphasizing the importance of continuous refinement to meet evolving user needs and ensure a lasting impact on public health.
Short-Term Benefits of High Protein, High Fiber Meal Replacements for Weight Loss in Overweight and Obese Adults
(2025) Chanchira Phosat; Akkarach Bumrungpert; Patcharanee Pavadhgul
Obesity is a critical global health issue that increases the risk for non-communicable diseases such as cardiovascular disease and diabetes. Dietary interventions like meal replacements are potential strategies for effective weight management. This randomized controlled trial aimed to evaluate the effects of high protein, high fiber meal replacement products on body composition, and gastrointestinal health in overweight and obese adults. The sixty-one participants (BMI 23.0 - 29.9 kg/m2) were randomly assigned to either a control group (n = 30) consuming a regular diet or a meal replacement (MRP) group (n = 31) consuming meal replacement once daily. Anthropometric data, dietary intake, and gastrointestinal health markers were assessed at baseline, week 2, and week 4. The results showed significant reductions in body weight (-0.8 ± 1.3 kg or -1.1% ± 1.8%, p = 0.004) and body mass index (-0.3 ± 0.5 kg/m2 or -1.1% ± 1.9%, p = 0.024) in the MRP group compared to the control group. The MRP group maintained a high level of protein intake with corresponding reductions in carbohydrate and fat intake (p < 0.01). However, no significant changes were found in body fat percentage or visceral fat. The MRP group experienced a notable decline in basal metabolic rate (p = 0.022), indicating potential metabolic adaptation to caloric restriction. Additionally, improvements in gastrointestinal health, specifically a reduced need for bowel movement assistance (p = 0.024), were observed in the MRP group. In conclusion, meal replacements were effective in promoting short-term weight loss and improving dietary patterns, though metabolic adaptations and fat loss require further exploration in longer-term studies.
The Relationships among Hospital Characteristics, Transformational Leadership, Safety Culture and Accreditation Status of Community Hospitals under the Office of the Permanent Secretary, Ministry of Public Health
(2025) Siwaporn Bunsake; Charuwan Tadadej; Jutatip Sillabutra
This study aims to investigatethe relationship among hospital characteristics, transformational leadership, safety culture and accreditation status of community hospitals under the Office of the Permanent Secretary, Ministry of Public Health. The sample included 536 participants who were in charge of quality management. Data were collected via questionnaires and analyzed using descriptive statistics, chi-square test statistics, and binary logistic regression to assess the relationships and influences of hospital characteristics, transformational leadership and safety culture and the accreditation status of community hospitals. The results indicated that directors of community hospitals scored highly in inspirational leadership (Mean = 4.05, S.D. = 0.69), and community hospitals demonstrated a high level of safety culture (Mean = 3.67, S.D. = 0.37). Both hospital level and safety culture were positively associated with the accreditation status of community hospitals (adjOR = 17.837, 6.189, p value = 0.000, 0.004). The F3-level hospitals were 17.837 times more likely to fail accreditation compared to hospitals at other levels (95%CI: 8.152, 39.025). Accredited hospitals were shown to have a safety culture that is 6.189 times higher than that of non-accredited hospitals (95%CI: 1.816, 21.095).
Enhanced Efficacy of Dane Fukang Decoction in Comparison to Conventional Treatments for Endometriosis
(2025) Preeyanuch Ketprathum; Hathaikan Chootrakool; Chuleekorn Sritonchai; Pichet Treewai
Endometriosis is a chronic gynecological disorder affecting millions of women worldwide, characterized by the growth of endometrial-like tissue outside the uterus. Conventional treatments, including hormonal therapies and surgery, often have limitations and side effects. This review explores the therapeutic potential of Dane Fukang decoction, a traditional Chinese herbal formula, in managing endometriosis. By examining this herbal remedy's pharmacological mechanisms, clinical evidence, and safety profile, we aim to provide a comprehensive understanding of its role in endometriosis treatment.The review discusses the multi-targeted actions of key herbs in Dane Fukang decoction, such as Radix Astragalus and Radix Angelicae Sinensis, which possess anti-inflammatory, anti-angiogenic, and immunomodulatory properties relevant to the pathophysiology of endometriosis. The clinical efficacy of Dane Fukang decoction in alleviating endometriosis symptoms, as demonstrated by higher total effective rates and fewer adverse reactions compared to conventional medications like gestrinone, is also highlighted
Quality of Working Life among Public Health Personnel in Sub-District Health Promoting Hospitals, Nakhon Pathom Province
(2025) Mawisa Sukpum; Youwanuch Sattayasomboon; Jutatip Sillabutra; Korravarn Yodmai
Quality of working life is a key factor that affects work efficiency and the retention of personnel in the healthcare system. This descriptive cross-sectional study aimed to assess the quality of work life (QWL) and investigate the relationships between personal characteristics, organizational climate, organizational support, and overall QWL among personnel working in sub-district health promoting hospitals (SHPH) in Nakhon Pathom province. A total of 297 persons (96.12% response rate), who have worked in SHPH for at least six months were included in this study. Data were collected from July 17 to August 31, 2023, using a self-administered questionnaire. Descriptive statistics, chi-square tests, Spearman’s rank correlation, and multiple linear regression were employed for data analysis, with a significance level set at 0.05. The results showed that the QWL was at a high level (Mean = 3.82, S.D. = 0.41). Social support (r = 0.746, p < 0.001) and organizational climate (r = 0.724, p < 0.001) were significantly associated with QWL. However, no significant association was found between personal characteristics and QWL. Social support and organizational climate were significant predictors of the QWL, jointly accounting for 66.9% of the variance in QWL (R2 adj = 0.669).The SHPH directors and public health administrators should focus on improving the organizational climate and social support through clear and practical policies to enhance the quality of working life among personnel.