Mahidol University's Institutional Repository
คลังสารสนเทศสถาบันของมหาวิทยาลัยมหิดล
"Wisdom Repository You Discover"
To collect Mahidol University's academic publications and intellectual properties more than 39 faculties
To present over 50,000 items of information in digital formats
To make it easy to access to all information at anytime, anywhere
Communities in Mahidol IR
Select a community to browse its collections.
Recent Submissions
Hypertension prevention behavior and its predictors among rural adults in Bangladesh: A community survey using the theory of planned behavior
(2026-05-01) Zeba S.A.; Haque M.; Alam M.A.; Al-Maqableh H.O.; Saha S.; Punthumus S.; Islam M.S.; Zeba S.A.; Mahidol University
Bangladesh faces a rising burden of non-communicable diseases (NCDs), with rural communities being particularly vulnerable due to limited healthcare access. Despite hypertension (HTN) being preventable, the disease is often overlooked in rural areas. This study aimed to assess health practices related to HTN prevention and its determinants among rural Bangladeshi adults using the theory of planned behaviour (TPB) and the World Health Organization's 4X4 NCD prevention model. A community-based survey was conducted with 355 rural participants selected via multi-stage sampling in the latter half of 2023. Data were collected through face-to-face interviews using a validated, pretested questionnaire. The average age of the respondents was 41.5 years, with 66.8% of them being male participants. The findings revealed inadequate knowledge, negative attitudes, and poor self-control regarding HTN prevention. Socioeconomic factors, including gender, income, education, and region, significantly influenced HTN prevention behaviors (p<0.05), while knowledge, attitude, and self-control were strongly linked to HTN prevention practices (p<0.05). The study’s causal model based on the TPB demonstrated a good fit, showing that attitude (β=0.34, p<0.001), motivation (β=0.16, p<0.05), and self-control significantly influenced intention (β=0.34, p<0.001), which strongly predicted hypertension prevention practices (β=0.54, p<0.001). Rural populations displayed reluctance to adopt healthy practices for HTN prevention. Enhancing community awareness and promoting behavioral change, therefore, should be prioritized in policy development to improve HTN prevention practices in rural Bangladesh.
Pre- and post-kidney transplant gnathostomiasis: Clinical manifestations, treatment, and outcomes
(2026-01-01) Watcharananan S.P.; Naitook N.; Prungrit U.; Aekkachaipitak N.; Lamjantuek P.; Boonnim K.; Mavichak V.; Watcharananan S.P.; Mahidol University
Gnathostomiasis (GNT) is a foodborne parasitic infection endemic to Southeast and East Asia. Its clinical relevance in transplant populations remains poorly defined. We assessed the clinical presentation, management, and outcomes of GNT in kidney transplant candidates and recipients in Thailand (2017-2023). Eighteen patients were identified (median age 51.5 years; 72.2% male), with 61.1% diagnosed at a median of 8.4 months posttransplant. Diagnosis was based on compatible clinical features and a positive Gnathostoma immunoblot test. Eosinophilia was more common in kidney transplant candidates than recipients (85.7% vs. 27.3%, P = .050). Posttransplant recipients predominantly presented with relative eosinophilia (72.7%), skin manifestations (36.4%), and leukopenia (36.4%). Strongyloidiasis coinfection occurred in 3 patients (16.7%), 2 of whom had gastrointestinal symptoms. All patients responded to antiparasitic therapy; however, 27.8% of patients required at least 1 retreatment course for persistent eosinophilic abnormalities. At 1 year after diagnosis of GNT, the median serum creatinine was 1.4 mg/dL (range, 0.7-11.8). Pretransplant cases had favorable posttransplant outcomes, with preserved graft function for 1 year. No deaths occurred. GNT is underrecognized in transplant recipients and often presents atypically, underscoring the need for clinical vigilance, evaluation for coinfection, and longitudinal posttreatment monitoring in endemic regions.
Association Between Perceptions of Educational Environment and Burnout Syndrome in Clinical Medical Students
(2026-07-01) Wongmaneewan S.; Thamwiriyakul N.; Wannapaschaiyong P.; Thamissarakul S.; Wongmaneewan S.; Mahidol University
Objective: Burnout syndrome is a critical concern among medical students, contributing to fatigue, reduced academic performance, and negative health outcomes. The educational environment is considered a key factor influencing burnout. This study aimed to assess medical students’ perceptions of their educational environment and its association with burnout syndrome. Material and Methods: A cross-sectional study was conducted at Chonburi Hospital, Thailand, from November to December 2023, involving 106 clinical medical students. Burnout syndrome was measured using the Maslach Burnout Inventory (MBI), and perceptions of the educational environment were evaluated using the Dundee Ready Education Environment Measure (DREEM). Data were analyzed using descriptive statistics, Pearson’s correlation, and regression analyses. Results: The mean DREEM score was 125.17±12.80, indicating an overall positive perception of the educational environment. The prevalence of burnout syndrome among participants was 50.94%. DREEM scores were significantly negatively correlated with burnout (r=-0.504, p-value<0.001), emotional exhaustion (r=-0.427, p-value<0.001), and depersonalization (r=-0.395, p-value<0.001). Subscales such as the Students’ Perception of Learning (SPL), Students’ Academic Self-Perception (SAP), Students’ Perception of Atmosphere (SPA), and Students’ Social Self-Perception (SSP) were also significantly negatively associated with burnout (all p-value<0.001). Multivariate analysis identified SPA and SSP as significantly associated factors of burnout. Conclusion: Medical students’ perceptions of the educational atmosphere and social support are significantly associated with burnout syndrome. Targeted efforts to improve these aspects of the educational environment may be effective in reducing burnout among clinical medical students.
Deformation-Induced Morphology Evolution of Protein-Lipid Aggregates and Its Relationship with Mechanical Properties of Vulcanized Natural Rubber
(2026-05-11) Zhang J.; Zhu Y.; Huang G.; Sakdapipanich J.; Xie Z.; Wu J.; Zhang J.; Mahidol University
The nonrubber components in natural rubber (NR), mainly proteins and lipids, are crucial for the outstanding comprehensive properties of NR through the formation of a naturally occurring network. However, how the morphology of nonrubber components changes during deformation and the effect of such changes on the mechanical properties of vulcanized NR remain unclear. Here, by using confocal laser scanning microscopy to track the morphology evolution of nonrubber components during deformation, the results reveal that the aggregates of proteins and lipids gradually disintegrate into smaller particles with increasing strain. This phenomenon represents the preferential collapse of a naturally occurring network under an externally applied load. Such a sacrificial characteristic of a naturally occurring network leads to energy dissipation, thereby enhancing the mechanical properties of vulcanized NR. The findings provide mechanistic insights into the structure–property relationship of NR, which can inspire the design of high-performance synthetic elastomers.
A case report of cutaneous Brugia pahangi infection presenting with recurrent lymphangitis and a subcutaneous nodule
(2026-06-01) Wongrat T.; Sitthinamsuwan P.; Sarasombath P.T.; Jirawattanadon P.; Wongpraparut C.; Wongrat T.; Mahidol University