Mahidol University's Institutional Repository

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Recent Submissions

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Understanding Research Approaches to Assess Sugar-Sweetened Beverage Taxation Policy Implementation and Response in Low- and Middle-Income Countries: Results From a Scoping Review
(2026-06-01) Phonsuk P.; Phulkerd S.; Jankhotkaew J.; Thow A.M.; Farrell P.; Phonsuk P.; Mahidol University
Implementing sugar-sweetened beverage (SSB) taxation policies presents significant challenges in practice, particularly in low- and middle-income countries (LMICs) where resources and capacity are often limited. Expanding the evidence base and knowledge on policy implementation and responses is crucial to identifying key drivers and barriers, as well as developing effective systems for monitoring and evaluation. This study aimed to identify the research approaches used to assess and analyze SSB tax policy implementation and responses at the national level. A scoping review was conducted, drawing on relevant literature from 5 databases—Medline, Web of Science, Scopus, Global Health, and CINAHL—covering publications from 2014 to 2023 inclusive. A total of 24 studies were included in the analysis. Two qualitative studies on policy implementation revealed limitations related to data access, with reliance on publicly available information. The remaining 22 studies, focusing on policy responses, primarily used quantitative methods to evaluate the reactions of industry, retailers, and consumers in terms of price adjustments, purchasing behavior, and consumption patterns. While there is substantial documentation on tax design and structure, enforcement dynamics, stakeholder interactions, and the complexities of policy implementation remain underexplored. This review highlights a critical gap in the research on the multifaceted nature of policy implementation and response. Future studies should prioritize these dynamics and adopt innovative methodologies to enhance the effectiveness of SSB taxation policies and public health interventions in LMICs.
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International Survey on Screening and Management of Strongyloidiasis in Solid Organ Transplant Patients
(2026-01-01) Simkins J.; Ravindra A.; Wolfe C.R.; Mularoni A.; Slavin M.; Ushiro-Lumb I.; Baddley J.W.; Hand J.; Pouch S.; Malinis M.; Freire M.P.; Radisic M.; Roberts M.B.; Tan B.H.; Watcharananan S.; Clemente W.T.; Simkins J.; Mahidol University
Background: Strongyloides stercoralis infection can be associated with high mortality in solid organ transplant (SOT) recipients, yet global practices regarding screening and management remain poorly characterized. We conducted an international survey to evaluate knowledge, screening, and management practices among healthcare workers (HCWs) involved in SOT care. Methods: We performed a cross-sectional, web-based survey of HCWs caring for SOT candidates and recipients. The survey assessed provider characteristics, knowledge of strongyloidiasis, as well as screening and management practices. Descriptive statistics were used to summarize responses. Results: A total of 101 HCWs responded, including 65 (64%) infectious diseases (ID) providers and 36 (36%) non-ID providers. Knowledge gaps were identified regarding transmission and mortality, particularly among non-ID providers. Overall, 85% of respondents reported screening SOT candidates for S. stercoralis; among those who screen, serology is the most commonly used method. Screening strategies varied by geographic region, with universal screening more common in endemic areas and targeted screening in non-endemic regions. Management practices, including approaches to indeterminate or negative test results, showed substantial heterogeneity. Conclusions: This international survey demonstrates considerable variability in knowledge, screening, and management of strongyloidiasis among HCWs involved in SOT care. These findings highlight opportunities for improved education, clearer guidance, and greater standardization of practices related to Strongyloides infection to avoid unnecessary morbidity. (Figure presented.).
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Biomechanical superiority of partial-thickness tendon split and bridging repair after BPTB graft harvest for ACL reconstruction
(2026-04-01) Saengpetch N.; Sawangworachat K.; Aroonjarattham P.; Kongmalai P.; Saengpetch N.; Mahidol University
Purpose: Reconstruction of the anterior cruciate ligament (ACL) with a bone–patellar tendon–bone (BPTB) autograft leaves a central tendon defect, and whether this should be repaired remains debated. Conventional suturing techniques often show limited biomechanical benefit. This study evaluated the biomechanical efficacy of a novel Partial-Thickness Split and Bridging Repair (PTSBR) technique compared with non-repair in a cadaveric model. Methods: Twelve knees from six fresh-frozen human cadavers were randomized to repair or non-repair groups. In the repair group, PTSBR involved a longitudinal partial-thickness incision with superficial tendon bridging and interrupted vertical mattress sutures. All specimens were mounted and tested using an Instron universal testing machine. Primary outcomes included maximal load, maximal stress, stiffness, Young's modulus, tendon dimensions, and failure location. Statistical comparisons were performed using paired analyses with significance set at p < 0.05. Results: PTSBR demonstrated significantly higher Young's modulus [90.19 MPa (24.02–202.47) vs. 50.83 MPa (19.96–115.29), p = 0.028] and maximal stress [19.35 MPa (5.21–35.54) vs. 13.30 MPa (5.21–24.23), p = 0.046] compared with non-repair. No difference was observed in maximal load (p = 0.674) or stiffness. Tendon thickness was significantly reduced in the repair group (2.34 ± 0.20 mm vs. 2.69 ± 0.32 mm, p = 0.023). Failure occurred mainly at the tibial or patellar attachment, with no mid-substance ruptures. Conclusion: The PTSBR technique enhanced tensile stiffness and stress resistance compared with non-repair, likely due to improved tendon fiber alignment and load-sharing. These biomechanical advantages suggest that PTSBR may represent a clinically relevant advancement in managing patellar tendon defects after BPTB graft harvest.
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From Needs Analysis to Instructional Design: Developing a Metacognitive Instructional Model for Teaching Workplace English Listening and Speaking in Thai Higher Education
(2026-01-01) Taladngoen U.; Watanapokakul S.; Taladngoen U.; Mahidol University
Metacognitive strategies can potentially develop EFL students’ English listening and speaking skills and foster metacognitive awareness and systematic, self-regulated learning. Nonetheless, metacognitive instruction has been limited to stand-alone interventions investigating listening or speaking skill development. Consequently, this mixed-methods study conducts a needs analysis—indispensable for instructional model development—to investigate the learning needs and target needs of 88 Thai EFL undergraduates, five Thai EFL teachers, and 28 employers, with the aim of developing a metacognitive instructional model for teaching workplace English listening and speaking at a Thai public university. Employing data and methodological triangulation, the instruments included online questionnaires, semi-structured interview questions, and a classroom observation protocol. Semi-structured interviews were conducted until data saturation was reached with fourteen undergraduates, five teachers, and four employers. Three randomly selected classrooms of the English for Working Skills course were observed twice. Data were analysed quantitatively and qualitatively. The findings revealed learning needs related to segregated-skill instruction and integrated-skill practice, incorporating diverse activities and integrating 21st-century skills. Target needs comprised necessities, lacks, and wants associated with workplace success. A theoretical, contextually informed metacognitive instructional model is then proposed, comprising in-class and out-of-class sections, with activities structured around the planning, monitoring, and reflecting phases to promote English communication and self-regulation.
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Possibility of Using Direct Current Potential Drop for Stress Corrosion Cracking Life Assessment
(2026-01-01) Phuraya N.; Navasalao P.; Panmongkol P.; Phung-On I.; Phuraya N.; Mahidol University
The standard tests for degree of sensitivity in Stainless Steel grade 304 are ASTM A262 and % DOS utilizing the DL-EPR technique. However, these methods are limited by their low resolution and challenges in classifying DOS when the grain boundary is particularly susceptible to corrosion. The direct current potential drop (DCPD) technique was used to determine the potential drop in solutionized specimens. These experimental specimens were sensitized by heating them at 650 °C for 1–32 h. The results reveal that the ASTM A262 showed microstructure examination for aging times greater than 2 h, and the sensitization was classified as just ditch structure. When DCPD was compared to DL-EPR, the potential drop initially dropped and then climbed to a high of 91.88 μV–96.83 μV and 78.32 –75.49 μV for solutionized specimens. At the same time, the DL-EPR technique’s DOS gradually increased, peaking at 40.86%. Nevertheless, due to the insufficient resolution to show a change in intergranular corrosion at the grain boundary, DOS stayed within the usual range of 38.82%. Conversely, the potential drop technique showed a steady decline, with the as-received and solutionized specimens showing 73.34 μV and 69.53 μV, respectively, as a result of the increased iron proportion in the matrix brought on by chromium replacing iron in the precipitated carbide. The outcomes demonstrated the benefit of employing the DCPD in comparison with conventional methods. It could also be used to determine the possibility that a crack would occur from stress corrosion cracking.