Publication: Results from the ARTEMIS DISK global antifungal surveillance study: A 6.5-year analysis of susceptibilities of candida and other yeast species to fluconazole and voriconazole by standardized disk diffusion testing
Issued Date
2005-12-01
Resource Type
ISSN
00951137
Other identifier(s)
2-s2.0-30744462355
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Clinical Microbiology. Vol.43, No.12 (2005), 5848-5859
Suggested Citation
M. A. Pfaller, D. J. Diekema, M. G. Rinaldi, R. Barnes, B. Hu, A. V. Veselov, N. Tiraboschi, E. Nagy, D. L. Gibbs, Jorge Finquelievich, David Ellis, Dominique Frameree, Annemarie Van Den Abeele, Jean Marc Senterre, Arnaldo Colombo, Robert Rennie, Steve Sanche, Bijie Hu, Yingchun Xu, Yingyuan Zhang, Nan Shan Zhong, Pilar Rivas, Angela Restrepo, Catalina Bedout, Ricardo Vega Matilde Mendez, Nada Mallatova, Eva Chmelarova, Julio Ayabaca, Jeannete Zurita, M. Mallie, E. Candolfi, W. Fegeler, A. Haase, G. Rodloff, W. Bar, V. Czaika, George Petrikos, Erzsébet Puskás, Ilona Doczi, Mestyan Gyula, Radka Nikolova, Uma Banerjee, Nathan Keller, Vivian Tullio, Gian Carlo Schito, Giacomo Fortina, Gian Piero Testore, Domenico D'Antonio, Giorgio Scalise, Pietro Martino, Graziana Manno, Kee Peng, Celia Alpuche, Eduardo Rodriguez Noriega, Mussaret Zaidi, Jacques F.G.M. Meis, Egil Lingaas, Danuta Dzierzanowska, Waclaw Pawliszyn, Mariada Luz Martins, Luis Albuquerque, Laura Rosado, Rosa Velho, Jose Amorim, Vera N. Ilina, Olga I. Kretchikova, Galina A. Klyasova, Sophia M. Rozanova, Irina G. Multykh, Nikolay N. Klimko, Elena D. Agapova, Natalya V. Dmitrieva, Abdul Mohsen Al-Rasheed, Jan Trupl, Leon Langsadl, Alena Vaculikova, Hupkova Helena, Denise Roditi, Anwar Hoosen, H. H. Crewe-Brown, M. N. Janse Van Rensburg, Adriano Duse, Kyungwon Lee, Mi Na Kim, A. Del Palacio, Aurora Sanchez-Sousa, Jacques Bille, K. Muhlethaler, Shan Chwen Chang, Jen Hsien Wang, Malai Vorachit, Deniz Gur, Volkan Korten, John Paul, Brian Jones, F. Kate Gould, Chris Kibbler, Nigel Weightman, Ian M. Gould, Ruth Ashbee Results from the ARTEMIS DISK global antifungal surveillance study: A 6.5-year analysis of susceptibilities of candida and other yeast species to fluconazole and voriconazole by standardized disk diffusion testing. Journal of Clinical Microbiology. Vol.43, No.12 (2005), 5848-5859. doi:10.1128/JCM.43.12.5848-5859.2005 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16732
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Results from the ARTEMIS DISK global antifungal surveillance study: A 6.5-year analysis of susceptibilities of candida and other yeast species to fluconazole and voriconazole by standardized disk diffusion testing
Author(s)
M. A. Pfaller
D. J. Diekema
M. G. Rinaldi
R. Barnes
B. Hu
A. V. Veselov
N. Tiraboschi
E. Nagy
D. L. Gibbs
Jorge Finquelievich
David Ellis
Dominique Frameree
Annemarie Van Den Abeele
Jean Marc Senterre
Arnaldo Colombo
Robert Rennie
Steve Sanche
Bijie Hu
Yingchun Xu
Yingyuan Zhang
Nan Shan Zhong
Pilar Rivas
Angela Restrepo
Catalina Bedout
Ricardo Vega Matilde Mendez
Nada Mallatova
Eva Chmelarova
Julio Ayabaca
Jeannete Zurita
M. Mallie
E. Candolfi
W. Fegeler
A. Haase
G. Rodloff
W. Bar
V. Czaika
George Petrikos
Erzsébet Puskás
Ilona Doczi
Mestyan Gyula
Radka Nikolova
Uma Banerjee
Nathan Keller
Vivian Tullio
Gian Carlo Schito
Giacomo Fortina
Gian Piero Testore
Domenico D'Antonio
Giorgio Scalise
Pietro Martino
Graziana Manno
Kee Peng
Celia Alpuche
Eduardo Rodriguez Noriega
Mussaret Zaidi
Jacques F.G.M. Meis
Egil Lingaas
Danuta Dzierzanowska
Waclaw Pawliszyn
Mariada Luz Martins
Luis Albuquerque
Laura Rosado
Rosa Velho
Jose Amorim
Vera N. Ilina
Olga I. Kretchikova
Galina A. Klyasova
Sophia M. Rozanova
Irina G. Multykh
Nikolay N. Klimko
Elena D. Agapova
Natalya V. Dmitrieva
Abdul Mohsen Al-Rasheed
Jan Trupl
Leon Langsadl
Alena Vaculikova
Hupkova Helena
Denise Roditi
Anwar Hoosen
H. H. Crewe-Brown
M. N. Janse Van Rensburg
Adriano Duse
Kyungwon Lee
Mi Na Kim
A. Del Palacio
Aurora Sanchez-Sousa
Jacques Bille
K. Muhlethaler
Shan Chwen Chang
Jen Hsien Wang
Malai Vorachit
Deniz Gur
Volkan Korten
John Paul
Brian Jones
F. Kate Gould
Chris Kibbler
Nigel Weightman
Ian M. Gould
Ruth Ashbee
D. J. Diekema
M. G. Rinaldi
R. Barnes
B. Hu
A. V. Veselov
N. Tiraboschi
E. Nagy
D. L. Gibbs
Jorge Finquelievich
David Ellis
Dominique Frameree
Annemarie Van Den Abeele
Jean Marc Senterre
Arnaldo Colombo
Robert Rennie
Steve Sanche
Bijie Hu
Yingchun Xu
Yingyuan Zhang
Nan Shan Zhong
Pilar Rivas
Angela Restrepo
Catalina Bedout
Ricardo Vega Matilde Mendez
Nada Mallatova
Eva Chmelarova
Julio Ayabaca
Jeannete Zurita
M. Mallie
E. Candolfi
W. Fegeler
A. Haase
G. Rodloff
W. Bar
V. Czaika
George Petrikos
Erzsébet Puskás
Ilona Doczi
Mestyan Gyula
Radka Nikolova
Uma Banerjee
Nathan Keller
Vivian Tullio
Gian Carlo Schito
Giacomo Fortina
Gian Piero Testore
Domenico D'Antonio
Giorgio Scalise
Pietro Martino
Graziana Manno
Kee Peng
Celia Alpuche
Eduardo Rodriguez Noriega
Mussaret Zaidi
Jacques F.G.M. Meis
Egil Lingaas
Danuta Dzierzanowska
Waclaw Pawliszyn
Mariada Luz Martins
Luis Albuquerque
Laura Rosado
Rosa Velho
Jose Amorim
Vera N. Ilina
Olga I. Kretchikova
Galina A. Klyasova
Sophia M. Rozanova
Irina G. Multykh
Nikolay N. Klimko
Elena D. Agapova
Natalya V. Dmitrieva
Abdul Mohsen Al-Rasheed
Jan Trupl
Leon Langsadl
Alena Vaculikova
Hupkova Helena
Denise Roditi
Anwar Hoosen
H. H. Crewe-Brown
M. N. Janse Van Rensburg
Adriano Duse
Kyungwon Lee
Mi Na Kim
A. Del Palacio
Aurora Sanchez-Sousa
Jacques Bille
K. Muhlethaler
Shan Chwen Chang
Jen Hsien Wang
Malai Vorachit
Deniz Gur
Volkan Korten
John Paul
Brian Jones
F. Kate Gould
Chris Kibbler
Nigel Weightman
Ian M. Gould
Ruth Ashbee
Other Contributor(s)
University of Iowa Carver College of Medicine
University of Texas Health Science Center at San Antonio
University of Wales
Zhongshan Hospital Shanghai
Institute of Antimicrobial Chemotherapy
Hospital de Clinicas Jose de San Martin
University of Szeged Faculty of Medicine
Giles Scientific, Inc.
Universidad de Buenos Aires
Women's and Children's Hospital Adelaide
CHU de Jumet
St Lucas Campus Heilige Familie
Centre Hospitalier Regional de La Citadelle
Universidade Federal de Sao Paulo
University of Alberta Hospital
Royal University Hospital
Universitario de Caracas
Peking Union Medical College
Huashan Hospital
Guangzhou Institute of Repiratory Disease
Inst. Nacional de Cancerologýa
CIB
Hospital Militar Central, Bogota
Hospital Ceske Budejovice
Krajska Hygienicka stanice se sidlem v Ostrave
Hospital FF. AA HG1
Hospital Vozandes
Universite de Montpellier
Institut de Parasitologie
Westfalische Wilhelms-Universitat Munster
Rheinisch-Westfalische Technische Hochschule Aachen
Inst. F. Med. Mikrobiologie
Carl-Thiem-Klinikum
Humaine Kliniken
Laikon General Hospital
BAZ County Institute
Szegedi Tudomanyegyetem (SZTE)
Pecsi Tudomanyegyetem
Szent Laszlo Hospital
All India Institute of Medical Sciences, New Delhi
Chaim Sheba Medical Center Israel
Universita degli Studi di Torino
Universita degli Studi di Genova
Ospedale di Novara
Universita degli Studi di Roma Tor Vergata
Ospedale Civile di Pescara
Instituto di Malattie Infettive
University of Malaya
Hospital General de Mexico
Universidad de Guadalajara
Hospital General O'Horan
Nijmegen Interdenominational Hospital Canisius-Wilhelmina
Rikshospitalet-Radiumhospitalet HF
Instytut Pomnik-Centrum Zdrowia Dziecka
Pracownia Bakteriologii
Universidade Nova de Lisboa, Instituto de Higiene e Medicina Tropical
Centro Hospitalar e Universitario de Coimbra
Instituto Nacional de Saude Dr. Ricardo Jorge
Hospital Geral de Santo Antonio
Novosibirsk Regional Hospital
Gen del Este Domingo Luciani
National Research Center for Hematology
City Clinical Hospital No.
Territory Center of Laboratory Diagnostics
Medical Mycology Research Institute
Irkutsk Regional Childrens Hospital
Oncology Research Center
Riyadh Military Hospital
National Cancer Center
NUTaRCH
Derer's University Hospital Slovakia
St. Cyril and Method's Hospital
Groote Schuur Hospital
Ga-Rankuwa Hospital
Baragwanath Hospital
University of the Free State
Johannesburg Hospital
Yonsei University
Asan Medical Center
Hospital 12 De Octobre
Hospital Ramon y Cajal
Centre Hospitalier Universitaire Vaudois
Universitat Bern
National Taiwan University Hospital
China Medical University Hospital Taichung
Mahidol University
Hacettepe Universitesi
Marmara Universitesi Tip Fakultesi
Royal Sussex County Hospital
Glasgow Royal Infirmary
Freeman Hospital
UCL
Friarage Hospital
Aberdeen Royal Infirmary
Leeds General Infirmary
Wayne State University
The Mount Sinai Medical Center
Weill Cornell Medical Center
Stanford University Medical Center
University Hospitals Case Medical Center
University of Virginia
Christiana Care
University of Texas Health Science Center at San Antonio
University of Wales
Zhongshan Hospital Shanghai
Institute of Antimicrobial Chemotherapy
Hospital de Clinicas Jose de San Martin
University of Szeged Faculty of Medicine
Giles Scientific, Inc.
Universidad de Buenos Aires
Women's and Children's Hospital Adelaide
CHU de Jumet
St Lucas Campus Heilige Familie
Centre Hospitalier Regional de La Citadelle
Universidade Federal de Sao Paulo
University of Alberta Hospital
Royal University Hospital
Universitario de Caracas
Peking Union Medical College
Huashan Hospital
Guangzhou Institute of Repiratory Disease
Inst. Nacional de Cancerologýa
CIB
Hospital Militar Central, Bogota
Hospital Ceske Budejovice
Krajska Hygienicka stanice se sidlem v Ostrave
Hospital FF. AA HG1
Hospital Vozandes
Universite de Montpellier
Institut de Parasitologie
Westfalische Wilhelms-Universitat Munster
Rheinisch-Westfalische Technische Hochschule Aachen
Inst. F. Med. Mikrobiologie
Carl-Thiem-Klinikum
Humaine Kliniken
Laikon General Hospital
BAZ County Institute
Szegedi Tudomanyegyetem (SZTE)
Pecsi Tudomanyegyetem
Szent Laszlo Hospital
All India Institute of Medical Sciences, New Delhi
Chaim Sheba Medical Center Israel
Universita degli Studi di Torino
Universita degli Studi di Genova
Ospedale di Novara
Universita degli Studi di Roma Tor Vergata
Ospedale Civile di Pescara
Instituto di Malattie Infettive
University of Malaya
Hospital General de Mexico
Universidad de Guadalajara
Hospital General O'Horan
Nijmegen Interdenominational Hospital Canisius-Wilhelmina
Rikshospitalet-Radiumhospitalet HF
Instytut Pomnik-Centrum Zdrowia Dziecka
Pracownia Bakteriologii
Universidade Nova de Lisboa, Instituto de Higiene e Medicina Tropical
Centro Hospitalar e Universitario de Coimbra
Instituto Nacional de Saude Dr. Ricardo Jorge
Hospital Geral de Santo Antonio
Novosibirsk Regional Hospital
Gen del Este Domingo Luciani
National Research Center for Hematology
City Clinical Hospital No.
Territory Center of Laboratory Diagnostics
Medical Mycology Research Institute
Irkutsk Regional Childrens Hospital
Oncology Research Center
Riyadh Military Hospital
National Cancer Center
NUTaRCH
Derer's University Hospital Slovakia
St. Cyril and Method's Hospital
Groote Schuur Hospital
Ga-Rankuwa Hospital
Baragwanath Hospital
University of the Free State
Johannesburg Hospital
Yonsei University
Asan Medical Center
Hospital 12 De Octobre
Hospital Ramon y Cajal
Centre Hospitalier Universitaire Vaudois
Universitat Bern
National Taiwan University Hospital
China Medical University Hospital Taichung
Mahidol University
Hacettepe Universitesi
Marmara Universitesi Tip Fakultesi
Royal Sussex County Hospital
Glasgow Royal Infirmary
Freeman Hospital
UCL
Friarage Hospital
Aberdeen Royal Infirmary
Leeds General Infirmary
Wayne State University
The Mount Sinai Medical Center
Weill Cornell Medical Center
Stanford University Medical Center
University Hospitals Case Medical Center
University of Virginia
Christiana Care
Abstract
© 2005, American Society for Microbiology. All Rights Reserved. Fluconazole in vitro susceptibility test results for 140,767 yeasts were collected from 127 participating investigators in 39 countries from June 1997 through December 2003. Data were collected on 79,343 yeast isolates tested with voriconazole from 2001 through 2003. All investigators tested clinical yeast isolates by the CLSI (formerly NCCLS) M44-A disk diffusion method. Test plates were automatically read and results were recorded with the BIOMIC Vision Image Analysis System. Species, drug, zone diameter, susceptibility category, and quality control results were collected quarterly via e-mail for analysis. Duplicate (the same patient, same species, and same susceptible-resistant biotype profile during any 7-day period) and uncontrolled test results were not analyzed. The 10 most common species of yeasts all showed less resistance to voriconazole than to fluconazole. Candida krusei showed the largest difference, with over 70% resistance to fluconazole and less than 8% to voriconazole. All species of yeasts tested were more susceptible to voriconazole than to fluconazole, assuming proposed interpretive breakpoints of ≥17 mm (susceptible) and ≤13 mm (resistant) for voriconazole. MICs reported in this study were determined from the zone diameter in millimeters from the continuous agar gradient around each disk, which was calibrated with MICs determined from the standard CLSI M27-A2 broth dilution method by balanced-weight regression analysis. The results from this investigation demonstrate the broad spectrum of the azoles for most of the opportunistic yeast pathogens but also highlight several areas where resistance may be progressing and/or where previously rare species may be "emerging".