Publication:
α-Glucosidase inhibitory, aromatase inhibitory, and antiplasmodial activities of a biflavonoid gb1 from garcinia kola stem bark

Issued Date

2010-02-25

Resource Type

Article

ISSN

14390221
00320943

DOI

10.1055/s-0029-1186081

Other identifier(s)

2-s2.0-77049113531

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Planta Medica. Vol.76, No.3 (2010), 276-277

Suggested Citation

Bassey S. Antia, Acharavadee Pansanit, Okon D. Ekpa, Udofot J. Ekpe, Chulabhorn Mahidol, Prasat Kittakoop α-Glucosidase inhibitory, aromatase inhibitory, and antiplasmodial activities of a biflavonoid gb1 from garcinia kola stem bark. Planta Medica. Vol.76, No.3 (2010), 276-277. doi:10.1055/s-0029-1186081 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/28781

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Title

α-Glucosidase inhibitory, aromatase inhibitory, and antiplasmodial activities of a biflavonoid gb1 from garcinia kola stem bark

Author(s)

Bassey S. Antia
 Acharavadee Pansanit
 Okon D. Ekpa
 Udofot J. Ekpe
 Chulabhorn Mahidol
 Prasat Kittakoop

Other Contributor(s)

Chulabhorn Research Institute
 University of Calabar
 Center for Environmental Health
 The Institute of Science and Technology for Research and Development, Mahidol University

Abstract

The biflavonoid, 3,4,4,5,5,7,7-heptahydroxy-3,8-biflavanone, known as GB1 (1), was isolated as a major constituent from Garcinia kola stem bark. GB1 (1) exhibited -glucosidase and aromatase inhibitory activities, as well as antiplasmodial activity, but was not toxic against cell lines tested. GB1 (1) may be a potential dietary supplement or phytomedicine for the prevention of breast cancer and type 2 diabetes mellitus. © Georg Thieme Verlag KG Stuttgart · New York.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Medicine
 Pharmacology, Toxicology and Pharmaceutics

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URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/28781

Collections

Scopus 2006-2010