Reliability of colour Doppler ultrasonography of the major salivary glands in Sjögren’s disease
Issued Date
2024-12-01
Resource Type
ISSN
0392856X
eISSN
1593098X
Scopus ID
2-s2.0-85213167784
Pubmed ID
39699869
Journal Title
Clinical and Experimental Rheumatology
Volume
42
Issue
12
Start Page
2476
End Page
2482
Rights Holder(s)
SCOPUS
Bibliographic Citation
Clinical and Experimental Rheumatology Vol.42 No.12 (2024) , 2476-2482
Suggested Citation
Sluijpers N.R.F., Fadhil M., Stel A.J., Dijkstra P.U., Spijkervet F.K.L., Arends S., Bootsma H., Vissink A., Delli K. Reliability of colour Doppler ultrasonography of the major salivary glands in Sjögren’s disease. Clinical and Experimental Rheumatology Vol.42 No.12 (2024) , 2476-2482. 2482. doi:10.55563/clinexprheumatol/ku5evp Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/102606
Title
Reliability of colour Doppler ultrasonography of the major salivary glands in Sjögren’s disease
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Abstract
Objective To analyse intraobserver and interobserver reliability of colour Doppler (CD) ultrasonography of the major salivary glands (SGUS) in patients clinically suspected of Sjögren’s disease (SjD). Methods One hundred consecutive outpatients visiting the University Medical Center Groningen for a diagnostic trajectory because of a suspicion of SjD were evaluated using CD ultrasonography of the submandibular and parotid salivary glands. All images were independently assessed by four observers (two experienced observers, one lesser experienced resident, one inexperienced trainee) in two sessions using the Outcome Measures in Rheumatology (OMERACT) CD scoring system (scale 0-3). A total score was calculated as the sum of the scores of the 4 glands (scale 0-12). Intra- and interobserver reliability, and reliability of live versus static scores were determined. Factors influencing variability in scores were analysed. Results Intraobserver weighted Cohen’s kappa’s of individual glands ranged from 0.23 (inexperienced observer) to 0.81 (experienced observer). Intraclass Correlation Coefficients (ICCs) for intraobserver reliability of the total CD score ranged from 0.53 (inexperienced observer) to 0.90 (experienced observer). The ICC for intraobserver reliability of live scoring compared to static images was 0.72. ICCs for interobserver reliability of the total CD score were 0.81 for session 1 and 0.71 for session 2. Patient variance was 74.1%, whereas residual variance contributed 15.5% to the total variance. Conclusion CD SGUS is a reliable imaging technique to visualise intraparenchymal vasculature in patients suspected of SjD, and therefore could be an asset in daily clinical practice. It requires, however, experience and prior training.