Browsing by Author "Faculty of Veterinary Medicine"

Filter results by typing the first few letters
Now showing 1 - 3 of 3
  • No Thumbnail Available
    PublicationMetadata only
    Calcium pre-exposure reducing histopathological alteration in nile tilapia (Oreochromis niloticus) after lead exposure
    (2009-09-21) P. Singhadach; W. Jiraungkoorskul; T. Tansatit; P. Kosai; C. Ariyasrijit; Center for Environmental Health; Toxicology Graduate Program; Mahidol University; Faculty of Veterinary Medicine
    This study was evaluated the influence of calcium to reduce the loxicily of sub-lethal lead concentration in Nile tilapia with emphasis on histopathological analysis. The values of 24, 48, 72 and 96 h LC 50of lead to tilapia were 247.51. 197.47. 183.74 and 182.38 mg L -1, respectively. Fish were pre-exposcd to vary dosages of calcium carbonate: 0 (Gl and G2); 20 (G3 and G4) and 60 (G5 and G6) mg L-1 for 4 days. After that, fish were post-exposed to 45 mg L -1 lead, which correspond to 25% of Ihe 96 h LC 50 (G2, G4 and G6) for 96 h. Histopathological changes were especially most evident in the group (G2) exposed to lead without calcium pre-exposure. The gills were observed edema, lamellar cell hyperplasia, epithelial lifting, lamellar fusion and aneurysm. There were blood congestion in sinusoids, vacuolation of hepatocytes and necrosis. Glomerulus's atrophy, tubular swelling and also necrosis were seen. However, the only observable lesion in the muscle was the infiltration of inflammatory cells and there were no histopathological changes observed in ihe brain and intesline of Ihe lead trealed fish. Fish with pre-exposed calcium (G4 and G6) showed slightly alteration when compare the only lead treatment groups. The results suggested that calcium pre-exposure may play an important role in the reduction of lead loxicitv in fish. © 2009 Academic Journals Inc.
  • No Thumbnail Available
    PublicationMetadata only
    Critical factors on chemical properties and heavy metals in water for livestock farms in Thailand
    (2013-01-01) Teeraporn Makaroon; Suwicha Kasemsuwan; Nattavut Ratanavanichrojn; Hathairad Hananantachai; Rachaneekorn Mingkhwan; Sutha Khaodhiar; Phitsanu Tulayakul; Faculty of Veterinary Medicine; Kasetsart University; Mahidol University; Chulalongkorn University
    This study aimed to investigate chemical quality of animal drinking used in livestock farms in Thailand. Samples and information from 68 pig farms, 35 chicken farms and 9 duckling farms were collected during March to August 2011. Water quality data were analyzed and compared with standard levels using the Mann-Whitney U and Wilcoxon Signed Rank Tests. Results revealed that median chemical values of water for livestock were generally within standard levels, except manganese and iron, which were detected in surfacewater with median values of 0.183 and 0.506 ppm, respectively, and are both higher than standard limits for drinking water. Median pH value in groundwater was 6.85, which was significantly (p < 0.05) lower than pH value (7.23) in surfacewater, and median level of hardness was 169.5 ppm in groundwater, which was significantly higher than that of surface water. Logistic regression was performed to identify a common source of water chemical contaminants and revealed that farms located outside the western region of Thailand and using surfacewater for their livestock were at risk of the high manganese levels in the water. Moreover, analyzed data from Department of Groundwater Resources of Thailand demonstrated high amount of hardness, manganese and iron in groundwater of Thailand, correlated with our findings. Thus, farms using surface or underground water should be aware of high level of manganese, iron and hardness.
  • No Thumbnail Available
    PublicationMetadata only
    Exercise increases brain-derived neurotrophic factor level in serum of horses
    (2015-01-01) Sasithorn Kongoun; Metha Chanda; Pawinee Piyachaturawat; Witchuda Saengsawang; Mahidol University; Faculty of Veterinary Medicine
    © 2015 Elsevier B.V. Serum-BDNF levels are known to reflect functions of the nervous system. It has been shown in humans that exercise increases serum-BDNF levels. However, how exercise training affects serum-BDNF in horses is unknown. Knowing how BDNF is altered in response to exercise training in horses will provide insight into the nervous system's response to exercise and may provide a novel indicator to improve the training program for sport horses. Here we investigated the effect of exercise on the level of serum-BDNF in horses by comparing BDNF levels in serum from sedentary horses to those from active horses that are trained and participated in polo matches. The level of total serum-BDNF was significantly higher in active horses compared with that of sedentary horses. Individual forms of BDNF (pro, truncated and mature BDNF) were also significantly higher in active horses, especially the truncated-BDNF. The findings suggest that exercise increases basal levels of horse serum-BDNF, indicating the positive response of the horse nervous system to physical activities.