Browsing by Author "John Estes"

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    Performance of the CRAFTi portable fluorometer comparing with the HPLC method for determining serum retinol
    (2011-08-01) Laksana Chaimongkol; Siwaporn Pinkaew; Harold C. Furr; John Estes; Neal E. Craft; Emorn Wasantwisut; Pattanee Winichagoon; Mahidol University; Prince of Songkla University; University of Wisconsin Madison; Craft Technologies
    Objective: To determine the performance of a portable fluorometer for measuring serum retinol (SR) concentration. Design and methods: Serum samples were obtained from 75 factory worker women and 143 school children. SR concentration was quantified using a portable fluorometer ('CRAFTi') and HPLC analysis. Results: SR by HPLC (1.23. ±. 0.43. μmol/L) and CRAFTi (1.16. ±. 0.46. μmol/L) was significantly correlated. Sensitivity and specificity were 85.3% and 78.0% (cutoff of 1.05. μmol/L). Kappa statistics showed moderate agreement. Conclusions: CRAFTi portable fluorometer is a promising field-friendly tool for screening vitamin A deficiency. © 2011 The Canadian Society of Clinical Chemists.