Browsing by Author "Josefin Ulriksdotter"

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    Contact dermatitis caused by glucose sensors—15 adult patients tested with a medical device patch test series
    (2020-01-01) Josefin Ulriksdotter; Cecilia Svedman; Magnus Bruze; Jenny Glimsjö; Kajsa Källberg; Thanisorn Sukakul; Martin Mowitz; Lunds Universitet; Helsingborgs Lasarett; Faculty of Medicine, Siriraj Hospital, Mahidol University; Blekingesjukhuset
    © 2020 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd. Background: Several cases of allergic contact dermatitis (ACD) to the glucose sensor FreeStyle Libre have been reported. Isobornyl acrylate (IBOA) and N,N-dimethylacrylamide (DMAA) are known culprit allergens. Objectives: To evaluate patients with suspected ACD to FreeStyle Libre in a standardized manner, present causative allergens, and assess patient-reported implications. Methods: A total of 15 patients with suspected ACD to FreeStyle Libre were patch tested with the Swedish baseline series and a new medical device series. IBOA and DMAA were tested at 0.1% and 0.3% in petrolatum (pet.). Readings were performed on day (D) 3 and D7. Background data, details on skin reactions, and associated implications were assessed using a questionnaire. Results: Thirteen patients were sensitized to IBOA and four to DMAA. Two positive reactions to IBOA and one to DMAA were seen only at 0.3% concentration on D7. Median duration of sensor use before dermatitis onset was 6 months. Half the number of the patients took precautions in everyday life due to sensor-related skin reactions. Six patients discontinued sensor usage. Conclusions: Patients with suspected ACD to glucose sensors should be evaluated with a relevant patch test series containing IBOA and DMAA. Adding the 0.3% pet. concentration is recommended. The reading on D7 is necessary.